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Laser Medicine

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Vol 21, No 1 (2017)
https://doi.org/10.37895/2071-8004-2017-21-1

CURRENT INFORMATION

ORIGINAL RESEARCHES

4-11 457
Abstract
Literature data and the author’s own experience with 388 patients have shown that infusions of autoblood irradiated with ultraviolet light is very effective for treating chronic arterial insufficiency of lower extremities. Clinical effectiveness of blood irradiated with ultraviolet light is manifested with prolonged distance of pain-free walk, partially or completely pain-free status at rest. In gangrene lesions, the demarcation process speeds up and postoperative wounds heal better. Radioisotopic and ultrasound examinations reveal better arterial blood flow in the diseased limb. Decreased blood viscosity, increased oxygenation of arterial blood as well as improved oxygen consumption in the ischemic tissue also lead to good clinical effect.
11-14 1231
Abstract
The researchers applied subcutaneous low-level laser irradiation of the thyroid gland in two groups of patients with subclinical hypothyroidism. Group 1 included 347 women aged 49.3 ± 7.3 with subclinical hypothyroidism caused by Hashimoto’s thyroiditis. Group 2 included 262 women aged 42 ± 6.8 with postoperative subclinical hypothyroidism (autoimmune process in the gland was stopped). All patients were prescribed a course of low-level laser therapy at the area of the thyroid gland with parameters: 2 W, wavelength 0.89 mcm, frequency 300 Hz, exposure time 5 min, 10 sessions. In a month, hypothyroidism developed in 10 (2.9%) patients in Group 1 and in 114 patients in Group 2 (43.5%). Cutaneous low-level laser irradiation of the thyroid gland is an effective and safe technique for treating subclinical hypothyroidism caused by the autoimmune thyroiditis.
14-17 169
Abstract
575 patients at various stages of alcoholic addiction disease were treated with a combined therapy including various photoautohemotherapy (PAHT) methods. Findings of clinical, laboratory and instrumental testings have proven PAHT effectiveness in patients with alcoholism. PAHT mechanisms are defined by PAHT multifactorial effects at patient’s organism which decrease alcoholic addiction and normalize functioning of organs affected by the disease. The developed and implemented PAHT technique consists of short blocking courses and has no complications which often develop after medicamentous therapy. Such treatment allows not only to achieve a stable remission in alcoholic patients but also to improve their quality of life.
17-24 339
Abstract
Purpose. To compare immediate and long-term results of LED laser light application for surgical interventions in tongue and oral cavity bottom tissues in patients with tongue and oral mucous cancer. 30 patients with the abovementioned pathology were taken into the study; 15 out of them were operated on with laser light having wavelength 970 nm emitted by laser device LSP IRE-Polus model LSP-0.97/10. In the study, certain criteria specifying the quality of surgical intervention with LED laser light were assessed. Research outcomes demonstrate that LED laser light in surgical interventions significantly reduces intraoperative blood loss, shortens the time on hemostasis stabilization during the surgery, positively affects the functional state of resected tissues which, in its turn, facilitates and shortens rehabilitation process in these patients.
24-26 147
Abstract
The researchers have analyzed long-term results of surgical treatment of 82 patients (61.2%) out of 134 patients with posttraumatic fistulas of the rectum who were treated with laser medical techniques. Complex surgical treatment with modern laser medical technologies reduced the rate of complications from 19.0% up to 7.9%, improved long-term results from 50.0% in controls up to 77.8% in the studied group and helped to achieve medical and social rehabilitation in 98 2% of patients comparing to 96.4% after traditional treatment.
27-29 205
Abstract
98 patients with stress urinary incontinence aged 37-62 were examined in the study. Microcirculation in their anterior vaginal wall before the treatment was investigated; control examination was made 1-1.5 months later after the treatment. To investigate microcirculation, laser-Doppler flowmetry with laser analyzer of blood microcirculation LAKK-02 (LAZMA, Russia) was made. Therapeutic session IncontiLase was made with Erbium laser «Fotona» (Slovenia). The findings obtained have demonstrated a significant improvement and normalization in microcirculatory flow indices after the treatment.
29-33 173
Abstract
Purpose. To study effects of red broad-band light of low intensity at the electrical activity and microstructure of the myocardium after its exposing to gamma-radiation. Materials and methods. White mongrel rats were consequently irradiated by gamma-rays (apparatus LUCH-1) and low-level broad-band light (red emitting diode, wavelength 630 nm, spectral half-height 20 nm). 54 experimental animals were taken into the study. The researchers studied changes in ECG and in the cardiomyocyte microstructure caused by ionizing radiation (control groups) and by consequent exposure to gamma- and light flow (experimental groups) as compared to intact animals. The myocardium microstructure was studied using electronic microscope Morgagni 268D. Results. There was a statistically significant increase in QT, QTc intervals and R- and T-waves stress in the control groups and restoration of their values in the studied groups to levels observed in intact animals. Changes in the electrical activity of the heart were accompanied with changes in the myocardium microstructure. The authors describe a way how to restore them to the values corresponding to intact animals using phototherapeutic procedures. Conclusion. Irradiation of the projection of the heart with low-intensity broadband red light, previously exposed to gamma radiation, allows to reduce manifestations of radiation sickness at the cellular and sub-cellular levels
33-38 227
Abstract
Purpose. To study the effectiveness of treatment of gun-shot wounds in soft tissues with photodynamic therapy (PDT) using Photoditazine microencapsulated form which is complexed with amphiphilic polymers and hydroxyapatite. Materials and methods. 70 non-linear rats were taken into the experimentation. Experimental animals were divided into four groups. In the control group, gun-shot wounds in soft tissues were treated with antiseptic bandages. In the first studied group (Group 1) gun-shot wounds were treated with PDT plus 0.5% Photoditazine water solution; in Group 2 - PDT plus Photoditazine complexed with amphiphilic polymers in gel form; in Group 3 - PDT plus Photoditazine in a microencapsulated form complexed with amphiphilic polymers and hydroxyapatite in gel form. Cytological, histological and microbiologic testings were performs in all animals. Results. PDT with Photoditazine complexed with amphiphilic polymers in gel or microcapsulated forms applied on gun-shot wounds leads to marked activation of wound purification from necrotized tissues, fibrin and microorganism colonies in the zone of primary wound canal. If to compare with PDT plus Photoditazine in water solution, one can see that in the zone of concussion there are less marked signs of microcirculatory disorders, less marked dystrophic and necrotic processes what lead, in the end, to less degree of the secondary necrosis in damaged tissues. Conclusion. Photodynamic therapy of gun-shot wounds in soft tissues using Photoditazine complexed with amphiphilic polymers in a gel or microencapsulated form is a highly effective technique which leads to outcomes considerably better than in traditional techniques what is also backed by findings obtained during cytological, histological and bacterial analyses.
38-41 196
Abstract
General anesthesia was performed in 93 patients (57 women and 36 men) aged 60 - 94 with concomitant diseases, such as IHD, HD of stages 2,3, risk 3, post-infarction cardiosclerosis, diabetes mellitus, bronchial asthma, etc. Two techniques of general anesthesia were used in this work: multimodal combined anesthesia potentiated with transcutaneous laser blood irradiation (TLBI) (main group - 61 patient) and traditional total intravenous anesthesia (32 patients). While analyzing findings of central and peripheral hemodynamics monitoring and bispectral indexes, the researchers concluded that the technique of general multimodal combined anesthesia potentiated with TLBI significantly reduces pharmacological loading at operated patients and stabilizes hemodynamic parameters in geriatric patients.
42-44 178
Abstract
Purpose. To study changes in blood microcirculation in patients with glossalgia after the irradiation with broad band red light. Materials and methods. 40 female volunteers were divided into control and experimental groups. In the control group there were 20 participants without the disease and in the experimental group there were 20 patients with glossalgia. Blood microcirculation in the tongue tissues located at the area of pain was measured in all of them. Laser Doppler flowmetry device and laser analyzer of the surface capillary blood flow «LAKK-01» were used for this. Level of pain was assessed with a descriptive scale of pain (Verbal Descriptor Scale). In the experimental group participants had sessions with red broad band light irradiation (source of radiation - light emitting diode, wavelength 630 nm, spectral half-width 20 nm). The painful zone in the tongue was irradiated every day for 20 days; exposure time - 3 minutes. Results. Before the treatment, microcirculation and pain levels in the experimental group were statistically different from the corresponding values in the control group (p < 0.001). The phototherapeutic treatment resulted in a marked decrease of these parameters up to the levels in the intact, control group. Conclusion. Exposure of painful zone in the tongue of patients with glossalgia to red broad band light may be recommended as a component of glossalgia therapy.

REVIEWS

45-48 419
Abstract
In the present literature review the authors analyze the state-of-art of modern endoscopic technologies utilized for colon examination. New diagnostic techniques which appeared in last decades -such as virtual chromoscopy, magnifying endoscopy, endosonography, autofluorescent diagnostics, confocal laser endomicroscopy- have significantly increased the importance of endoscopic examinations. In the article, one also can find data which back the effectiveness of virtual chromoendoscopy in endoscopic diagnostics of colon neoplasms. The virtual chromoscopy is aimed to improve a detailed examination of surface structures, capillary network what can be achieved due to optical filters and post-computer image processing. The virtual chromoscopy is an effective technique of endoscopic diagnostics of tumors in the colon. However, there still remains a number of unsolved issues on its application which need further research and perfection.

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ISSN 2071-8004 (Print)
ISSN 2686-8644 (Online)