Photodynamic therapy for treating vulvar lichen sclerosus
https://doi.org/10.37895/2071-8004-2024-28-2-41-46
Abstract
Vulvar lichen sclerosus (VLS) is a chronic inflammatory dystrophic disease affecting the external genitalia, significantly deteriorating the woman’s quality of life and producing an extremely negative effect at her mental status. In case of inefficacy and/or contraindications to traditional pharmacological therapy, modern non-invasive apparatus-based treatment can serve as an alternative. Among them is photodynamic therapy (PDT) which affects targeting tissues with a proper photosensitizing agent and a direct irradiation with light of a specific wavelength. The authors describe their experience in treating 28 patients with VLS who had a course of three PDT sessions. As a result, 82 % of them had a complete symptom remission with no serious adverse effects and excellent therapy tolerance.
About the Authors
I. A. Apolikhina
V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology; I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Inna А. Apolikhina – Dr. Sci. (Med.), Professor, head of the department of aesthetic gynecology and rehabilitation; professor
Moscow
A. S. Saidova
V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology
Russian Federation
Russian Federation
Ayna S. Saidova – Cand. Sci. (Med.), obstetrician-gynecologist at the department of aesthetic gynecology and rehabilitation
Moscow
T. A. Teterina
V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology
Russian Federation
Russian Federation
Tatiana А. Teterina – obstetrician-gynecologist at the department of aesthetic gynecology and rehabilitation
Moscow
A. E. Bychkova
V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology
Russian Federation
Russian Federation
Anastasia Е. Bychkova – obstetrician-gynecologist, oncologist at the department of aesthetic gynecology and rehabilitation
Moscow
E. A. Gorbunova
V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology
Russian Federation
Russian Federation
Elena А. Gorbunova – Dr. Sci. (Med.), obstetrician-gynecologist, physical therapist, researcher at the department of aesthetic gynecology and rehabilitation
Moscow
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Review
For citations:
Apolikhina I.A., Saidova A.S., Teterina T.A., Bychkova A.E., Gorbunova E.A. Photodynamic therapy for treating vulvar lichen sclerosus. Laser Medicine. 2024;28(2):41-46. (In Russ.) https://doi.org/10.37895/2071-8004-2024-28-2-41-46
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