Perspectives for Ytterbium porphyrin complexes in clinical practice

Abstract

Purpose. To study possibilities of ytterbium porphyrin complexes (IPC) with luminescence in the infrared range of the spectrum for differential diagnostics of various neoplasms and for controlling some pathological processes. Materials and methods. In the presented work the authors used experimental and clinical finings which characterize IPC as effective luminophores having the tropism to changed tissues with prevailing proliferative and inflammatory processes. In the experimental studies mice with inoculated Lewis carcinoma and different ways of ICP administration were used. Some patients with non-oncologic lesions were externally applied medicinal compositions on their skin and mucous too. Results. As it has been shown, ICP may be effectively applied for the above mentioned purposes using various ways of administration: intravenous, intracavital, peroral and external.