Photodynamic therapy for periprosthetic joint infection
A. I. Guseynov,
А. V. Baranov,
A. A. Radzhabov,
V. A. Derbenev,
V. I. Karandashov,
N. P. Alexandrova https://doi.org/10.37895/2071-8004-2021-25-1-9-15
Abstract
Introduction. The increase in the number of patients with joint and hip diseases is an actual problem in the clinical medicine. Objective: to improve outcomes of the combined surgical treatment of patients with deep periprosthetic infection (PPI) by developing and improving surgical techniques using spacers and laser technologies.
Material and methods. Thirty-five patients with suppurated large joints as a complication after their replacement were examined and treated. In 9 (25.7 %) patients, PPI developed within 3–12 months after the primary arthroplasty. Twenty (57.1 %) patients developed PPI within 1–2 years after the surgery. In 4 (11.4 %) cases, suppuration in the endoprosthetic area developed in 2–3 years, and in 2 (5.7 %) patients – in 3–3.5 years. The age of the patients was 47–70 years. The main group consisted of 20 patients, the control group – of 15 patients. Patients from the main group had laser photodynamic therapy (PDT) session after the removal of endoprosthetic elements and devitalized tissues.
Results. Patients from the main group had uneventful postoperative course – less pain syndrome, rapid resolution of the infl ammatory process, wound healing by the primary tension.
Conclusion. Application of a new intraoperative PDT technique, developed by the authors, promotes rapid resolution of purulent-infl ammatory process and better healing of postoperative wounds by primary tension.
About the Authors
A. I. Guseynov
Hospital for War Veterans N 2, Department of Moscow Healthcare;
Skobelkin State Scientifi c Center of Laser Medicine, FMBA of Russia
Russian Federation
Russian Federation
Guseynov Ali – MD, Cand. Sc. (Med.), Chief of the Department of Purulent Surgery
Moscow
А. V. Baranov
Skobelkin State Scientifi c Center of Laser Medicine, FMBA of Russia
Russian Federation
Russian Federation
Baranov Alexey – MD, Dr. Sc. (Med.), Director of Skobelkin State Scientifi c Center of Laser Medicine
Moscow
A. A. Radzhabov
Hospital for War Veterans N 2, Department of Moscow Healthcare;
Skobelkin State Scientifi c Center of Laser Medicine, FMBA of Russia
Russian Federation
Russian Federation
Radzhabov Abdugani – MD, Dr. Sc. (Med.), Head of the Department of Surgical Infection
Moscow
V. A. Derbenev
Skobelkin State Scientifi c Center of Laser Medicine, FMBA of Russia
Russian Federation
Russian Federation
Derbenev Valentin – MD, Dr. Sc. (Med.), Professor, Chief Researcher in the Department of Surgical Infection
Moscow
V. I. Karandashov
Skobelkin State Scientifi c Center of Laser Medicine, FMBA of Russia
Russian Federation
Russian Federation
Karandashov Vladimir – MD, Dr. Sc. (Med.), Professor, Head of Department of Laser Biotechnologies and Clinical Pharmacology
Moscow
N. P. Alexandrova
Moscow Scientifi c-Practical Center of Medical Rehabilitation, Restorative and Sports Medicine, Department of Moscow Healthcare
Russian Federation
Russian Federation
Alexandrova Natalia – MD, Dr. Sc. (Biol.), Professor, Leading Researcher in Department of Medical Rehabilitation
Moscow
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Review
For citations:
Guseynov A.I., Baranov А.V., Radzhabov A.A., Derbenev V.A., Karandashov V.I., Alexandrova N.P. Photodynamic therapy for periprosthetic joint infection. Laser Medicine. 2021;25(1):9-15. (In Russ.) https://doi.org/10.37895/2071-8004-2021-25-1-9-15
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