Combined treatment of venous ulcers in chronic diseases of lower extremity veins

Abstract

The aim of the present study was to compare results of combined application of low-intensive laser irradiation, fine-dispersion drug irrigation of venous ulcers and surgical correction of venous hemodynamics in 160 patients with chronic venous diseases of class C6. 102 (63.7%) patients from Group 1 had a combined therapy - laser irradiation and fine dispersion drug irrigation. In Group II (n = 58) patients had a conventional treatment. On day 5 in Group I one could see a decrease of microbial contamination from 10⁷-10⁸ to 10⁴-10⁵ (p < 0.05), and on day 20 - no contamination. Epithelisation dynamic parameters prevailed in Group I more than by two folds (p < 0.05). Surface purification, granulations and the onset of epithelisation were seen on days 4.2 ± 1.1 and 9.6 ± 1.3; 5.9 ± 0.8 and 13.1 ± 2.1; 8.9 ± 1.2 and 23.3 ± 1.6, respectively. Complete epithelisation in patients from Group I and Group II was in 29.1 ± 0.7 and 46.2 ± 0.8 days (p < 0.05). 12 months later after the conservative treatment the recurrence of trophic ulcers was seen in 34.8% in Group I and in 66.7% in Group II. Preoperative measures in Group I reduced the preoperative period by 2.8 folds. Complete intake of autodermograft in Group I was achieved in 75% of cases, in Group II - in 32.3%. Combined application of low-intensive laser irradiation and fine- dispersion drug irrigation is a pathogenic non-invasive technique for the conservative treatment and preoperative preparation in C6 class patients.