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Multimodal general anaesthesia based on acupane, paracetamol and ketarol potentiated with transcutaneous laser blood irradiaiton

https://doi.org/10.37895/2071-8004-2016-20-4-37-41

Abstract

Purpose. To conduct a comparative study of two techniques protecting patients from the surgical aggression: multimodal combined anesthesia with transcutaneous laser blood irradiation (TLBI) and total intravenous anesthesia. Materials and Methods. 58 patients (43 women and 15 men), aged 23-79 who underwent laparoscopic cholecystectomy (n - 45) and phlebectomy (n - 13) had anaesthesiologic support during their surgeries. Patients were divided into two groups (control and studied). In the studied group (32 patients) the anesthesia was multimodal and combined added with TLBI ; in the control group (26 patients) the anesthesia was general, total, intravenous. Conclusion. A comparative analysis of the obtained data on the monitoring of peripheral and central hemodynamics and bispectral index has shown that the combined application of non-narcotic analgetics (Acupan, Paracetamol, Ketorol) and TLBI can replace narcotic analgetics in the modern multimodal anaesthesia so as to protect the human organism of surgical aggression.

About the Authors

V. S. Shiriaev
ФГБУ «ГНЦ лазерной медицины ФМБА России»
Russian Federation


L. V. Musikhin
ФГБУ «ГНЦ лазерной медицины ФМБА России»
Russian Federation


F. M. Shvetsky
ФГБУ «ГНЦ лазерной медицины ФМБА России»
Russian Federation


V. A. Bubnov
ФГБУ «ГНЦ лазерной медицины ФМБА России»
Russian Federation


E. I. Sazhenina
ФГБУ «ГНЦ лазерной медицины ФМБА России»
Russian Federation


A. M. Khosrovyan
ФГБУ «ГНЦ лазерной медицины ФМБА России»
Russian Federation


T. L. Airapetova
ФГБУ «ГНЦ лазерной медицины ФМБА России»
Russian Federation


M. A. Grebenkina
ФГБУ «ГНЦ лазерной медицины ФМБА России»
Russian Federation


M. V. Yumashina
ФГБУ «ГНЦ лазерной медицины ФМБА России»
Russian Federation


References

1. Авруцкий М.Я., Калиш Ю.И., Мадартов К.М., Мусихин Л.В. Внутрисосудистое лазерное облучение крови при анестезии и послеоперационной интенсивной терапии. - Ташкент: Изд-во мед. лит-ры им. Абу ибн Сино, 1997. - 151 с.

2. Авруцкий М.Я., Ширяев В.С., Смольников П.В. Морадол (буторфанол-тартрат) в анестезиологии. - М.: Издательство стандартов, 1990. - 146 с.

3. Гайтон А. Физиология кровообращения. Минутный объем сердца и его регуляция. - М.: Медицина, 1969. - 320 с.

4. Мещеряков А.А., Перов О.И., Скобелев Е.И. и др. Оптимизация анестезии на плановых операциях холецистэктомии у пожилых больных // Новости анестезиологии и реаниматологии. -2006. - № 1. - С. 81-82.

5. Москвин С.В., Буйлин В.А. Основы лазерной терапии. - Тверь, 2006. - С. 256.

6. Перов О.И., Бугровская О.И., Городовикова Ю.А., Смольников П.В. Особенности центральной гемодинамики у пациентов пожилого возраста при общей анестезии севофлюраном // Общая реаниматология. - 2011. - Т. 7. - № 3. - С. 5-8.

7. Du Manoir B. et al. Randomized prospective study of the analgesic effect of nefopam after orthopaedic surgery // Br. J. Anaesthesia. -2003. - Vol. 91. - P. 836-841.

8. Evans M.S. et al. Nefopan for the prevention of postoperative pain: quantitative systematic review // Br. J. Anaesthesia. - 2008 Nov. - Vol. 101 (5). - P. 610-617.

9. Girard P. et al. Role of catecholamines and serotonin receptor subtypes in nefopam-induced anti-nociception // Pharmacological research. - 2006. - Vol. 54. - P. 195-202.

10. Huang Y.Y., Chen A.C. et al. Biphasic dose response in low level light therapy. - University of Massachusetts, 2009. - 18 p.

11. Kapfer B. et al. Nefopam and ketamin Comparably Enhance Postoperative Analgesia // Anestesia & Analgesia. - 2005. -Vol. 100. - P. 169-174.

12. Kehlet H., Dahl G.B. The value of “multimodal” or “Balanced analgesia” postoperative pain treatment // Anesth. & Analg. -1993. - Vol. 77950. - P. 1048-1056.

13. Kehlet H., Jensen T.S., Woolf C.J. Persistent postsurgical pain: risk factor and prevention // Lancet. - 2006. - Vol. 367. -P. 1616-1618.

14. King P.R. Low level laser therapy: a review // Lasers in Medical Science. - 1989. - Vol. 4 (2). - P. 141-150.

15. Mimoz O. et al. Analgesic efficacy and safety of nefopan vs. propacetamol following hepatic resection // Anaesthesia. - 2001 Jun. - Vol. 56 (6). - P. 520-525.

16. Rouds D.E., Chamberian E.C., Okinaki I. Laser radiation of tissue cultures // Ann. N.Y. Acad Sci. - 1965. - Vol. 28 (122). -P. 713-727.

17. Tirault M. et al. The Effect of Morfine Overconsumption Induced by Large-Dose Remifentanyl During Propofol Anestesia for Major Abdominal Surgery // Anesth. & Analg. - 2006. - Vol. 102. -P. 110-117.

18. Tramoni G. et al. Morphine-sparing effect by continuous injection after abdominal surgery by laparotomy // Eur. J. Anaesthesia. - 2003. - Vol. 20. - P. 990-992.

19. Verleye M. et al. Nefopam blocks voltage sensitive channels and modulates glutamatergic transmission in rodents // Brain. Res. - 2004. - Vol. 1013. - P. 249-255.


Review

For citations:


Shiriaev V.S., Musikhin L.V., Shvetsky F.M., Bubnov V.A., Sazhenina E.I., Khosrovyan A.M., Airapetova T.L., Grebenkina M.A., Yumashina M.V. Multimodal general anaesthesia based on acupane, paracetamol and ketarol potentiated with transcutaneous laser blood irradiaiton. Laser Medicine. 2016;20(4):37-41. (In Russ.) https://doi.org/10.37895/2071-8004-2016-20-4-37-41

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ISSN 2071-8004 (Print)
ISSN 2686-8644 (Online)