Application of confocal laser endomicroscopy in the diagnosis of benign tumors of the colon
https://doi.org/10.37895/2071-8004-2018-22-4-28-33
Abstract
Confocal laser endomicroscopy is a rapidly developing direction that allows to create a bridge between endoscopy and histological examination in the real-time mode. This latest technology has made it possible to study the microstructure of mucous membrane of gastrointestinal tract in vivo during endoscopic examination (“virtual biopsy”) and is of increasing interest in clinical practice. To study colon, confocal endomicroscopy is justified for the differential diagnostics of polyps and assessment of colon state in patients with inflammatory bowel diseases.
About the Authors
N. V. MokshinaRussian Federation
Moscow
N. A. Solovyеv
Russian Federation
Moscow
D. V. Sazonov
Russian Federation
Moscow
D. N. Panchenkov
Russian Federation
Moscow
F. G. Zabozlaev
Russian Federation
Moscow
References
1. Vetshev P.S., Stoyko Yu.M., Krylov N.N. Prevention, diagnosis and treatment of colon neoplasms. Rossyisky zhurnal gasrtoenterologii, gepatologii i koloproktologii. 2005, 15 (1): 6–91.
2. Davydov M.I., Axel E.M. Mortality from malignant neoplasms. Vestnik RCRC named after Blokhin. 2011; 22 (3–1): 93–123.
3. Zavyalov D.V., Kashin S.V. Overlooked colon neoplasia. Coloproctologia. 2015; 51 (1): 32–37.
4. Khrustaleva M.V., Khodakovskaya Yu.A., Godzhello E.A., Dekhtyar M.A., Bulganina N.A., Grishina E.A., Titova I.V., Fedorov D.N., Morozova M.M. Technology of spectral color selection in the assessment of morphological structure of intestinal polyps. Medicinsky sovet. 2018; 3: 91–96.
5. Buchner A.M., Shahid M.W., Heckman M.G. et al. Comparison of probe-based confocal laser endomicroscopy with virtual chromoendoscopy for classifcation of colon polyps. Gastroenterology. 2010; 138: 834–842.
6. Huang C.S., O’Brien M.J., Yang S. et al. Hyperplastic polyps, serrated adenomas, and the serrated polyp neoplasia pathway. Am. J. Gastroenterol. 2004; 99: 2242–2255.
7. Kang H.Y., Kim Y.S., Kang S.J., Chung G.E., Song J.H., Yang S.Y. et al. Comparison of Narrow Band Imaging and Fujinon Intelligent Color Enhancement in Predicting Small Colorectal Polyp Histology. Digestive Diseases and Sciences. 2015; 60 (9): 2777–2784.
8. Kiesslich R., Fritsch J., Holtmann M., Koehler H.H., Stolte M., Kanzler S., Nafe B., Jung M., Galle P.R., Neurath M.F. Methylene blue-aided chromoendoscopy for the detection of intraepithelial neoplasia and colon cancer in ulcerative colitis. Gastroenterology. 2003; 124: 880–888.
9. Rex D.K., Helbig C.C. High yields of small and flat adenomas with high-defnition colonoscopes using either white light or narrow band imaging. Gastroenterology. 2007; 133: 42–47.
10. Sanduleanu S., Driessen A., Gomez-Garcia E., Hameeteman W., de Bruïne A., Masclee A. In vivo diagnosis and classifcation of colorectal neoplasia by chromoendoscopy – guided confocal laser endomicroscopy. Clin. Gastroenterol. Hepatol. 2010; 8: 371–378.
11. Sauk J., Hoffman A., Anandasabapathy S., Kiesslich R. Highdefnition and flteraided colonoscopy. Gastroenterol. Clin. North. Am. 2010; 39: 859–881.
12. Shahid M.W., Buchner A.M., De Melo S.W. et al. Comparison of real time versus offline-blinded accuracy of confocal laser endomicroscopy (pCLE) for diagnosis of neoplasia on colorectal polyps. Gastrointestinal Endoscopy. 2010; 71: AB199.
13. Ussui V.M., Wallace M.B. Confocal endomicroscopy of colorectal polyps. Gastroenterol. Res. Pract. 2012: 545–679.
14. Wallace M.B., Fockens P. Probe-based confocal laser endomicroscopy. Gastroenterology. 2009; 136: 1509–1513.
Review
For citations:
Mokshina N.V., Solovyеv N.A., Sazonov D.V., Panchenkov D.N., Zabozlaev F.G. Application of confocal laser endomicroscopy in the diagnosis of benign tumors of the colon. Laser Medicine. 2018;22(4):28-33. (In Russ.) https://doi.org/10.37895/2071-8004-2018-22-4-28-33