goslasmedЛазерная медицинаLaser Medicine2071-80042686-8644Skobelkin Centre for Laser Medicine - a branch of the Federal Clinical Center for High Medical Technologies, FMBA of Russia10.37895/2071-8004-2016-20-2-54-56goslasmed-87Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL RESEARCHESПодавление роста штаммов золотистого стафилококка светом низкоинтенсивного красного лазераSuppression of staphylococcus aureus growth by low-intensity red laser lightБрилльГригорий ЕфимовичBrillG. E.gbrill@yandex.ruЕгороваА. В.EgorovaA. V.noemail@neicon.ruТучинаЕ. С.TuchinaE. S.noemail@neicon.ruБугаеваИ. О.BugaevaI. O.noemail@neicon.ruМорозовО. А.MorozovO. A.noemail@neicon.ruГБОУ ВПО «Саратовский государственный медицинский университет им. В.И. Разумовского» Минздрава РоссииРоссияФГБОУ ВПО «Саратовский государственный университет им. Н.Г. Чернышевского»Россия2016030820182025456Copyright © Брилль Г.Е., Егорова А.В., Тучина Е.С., Бугаева И.О., Морозов О.А., 20182018Брилль Г.Е., Егорова А.В., Тучина Е.С., Бугаева И.О., Морозов О.А.Brill G.E., Egorova A.V., Tuchina E.S., Bugaeva I.O., Morozov O.A.This work is licensed under a Creative Commons Attribution 4.0 License.https://goslasmed.elpub.ru/jour/article/view/87

Целью настоящей работы явилось изучение принципиальной возможности подавления роста различных штаммов золотистого стафилококка светом низкоинтенсивного красного лазера с длиной волны 660 нм. В качестве объекта исследования использовались клетки метициллин-чувствительного и метициллин-резистентного штаммов золотистого стафилококка. Для облучения применялся полупроводниковый лазер, генерирующий линейно-поляризованное излучение красной области спектра (X - 660 нм). Плотность мощности составляла 100 мВт/см2, время облучения - 5, 10, 15 и 30 мин, энергетическая экспозиция - соответственно 30, 60, 90 и 180 Дж/см2. Установлено, что низкоинтенсивное лазерное излучение оказывает ингибирующее влияние на рост колоний как метициллин-чувствительного, так и метициллин-резистентного штаммов золотистого стафилококка, причем резистентный штамм обладает более высокой чувствительностью к действию красного света, поскольку бактериостатический эффект выявляется при действии более низких доз облучения.

Purpose. To study evident abilities of low-intensity red laser light with wavelength 660 μm to inhibit the growth of various strains of Staphylococcus aureus. Materials and methods. Methicillin-sensitive and methicillin-resistant strains of Staphylococcus aureus were used as studied objects. Semiconductor laser generating linear polarized light in the red spectral region (X - 660 nm) was used for irradiation. Power density was 100 mW/cm2, exposure time - 5, 10, 15 and 30 min, heat density was 30, 60, 90 and 180 J/cm2, respectively. Results. It has been found out that low-intensity laser radiation has an inhibitory effect at the growth of both methicillin-sensitive and methicillin-resistant strains of Staphylococcus aureus. The resistant strain is more sensitive to red laser light as the bacteriostatic effect is seen at lower doses.

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The authors declare that there are no conflicts of interest present.