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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">goslasmed</journal-id><journal-title-group><journal-title xml:lang="ru">Лазерная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Laser Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8004</issn><issn pub-type="epub">2686-8644</issn><publisher><publisher-name>Skobelkin Centre for Laser Medicine - a branch of the Federal Clinical Center for High Medical Technologies, FMBA of Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37895/2071-8004-2021-25-3-40-46</article-id><article-id custom-type="elpub" pub-id-type="custom">goslasmed-737</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>Инфракрасное лазерное воздействие в комбинации с приемом аминокислот с разветвленной боковой цепью стимулирует физиологическую адаптацию скелетных мышц</article-title><trans-title-group xml:lang="en"><trans-title>Infrared laser exposure in combination with branchedchain amino acid stimulates physiological adaptation of skeletal muscles</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8994-570X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галлямутдинов</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gallyamutdinov</surname><given-names>R. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галлямутдинов Ростислав Винерович – научный сотрудник.</p><p>Челябинск</p></bio><bio xml:lang="en"><p>Rostislav Gallyamutdinov – Researcher.</p><p>Chelyabinsk</p></bio><email xlink:type="simple">rkenpachi@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6343-7563</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Головнева</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovneva</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Головнева Елена Станиславовна – доктор медицинских наук, доцент, заместитель директора по научно-исследовательской работе, ГБУЗ Многопрофильный ЦЛМ; профессор кафедры нормальной физиологии, Южно-Уральский ГМУ.</p><p>Челябинск</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8227-1247</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ревель-Муроз</surname><given-names>Ж. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Revel-Muroz</surname><given-names>Zh. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ревель-Муроз Жан Александрович – доктор медицинских наук, директор.</p><p>Челябинск</p></bio><bio xml:lang="en"><p>Revel’-Muroz Zhan – Dr. Sc. (Med.), Director.</p><p>Chelyabinsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7505-2436</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Еловских</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Elovsky</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Еловских Инна Владиславовна – кандидат медицинских наук, доцент кафедры патологической анатомии.</p><p>Челябинск</p></bio><bio xml:lang="en"><p>Inna Elovskih – Cand. Sc. (Med.), Associate Professor at the Department of Pathological Anatomy.</p><p>Chelyabinsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ГБУЗ Многопрофильный центр лазерной медицины<country>Россия</country></aff><aff xml:lang="en">Multidisciplinary Center of Laser Medicine<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ГБУЗ Многопрофильный центр лазерной медицины; ФГБOУ ВО Южно-Уральский государственный медицинский университет Минздрава России<country>Россия</country></aff><aff xml:lang="en">Multidisciplinary Center of Laser Medicine; Southern Ural State Medical University<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>22</day><month>01</month><year>2022</year></pub-date><volume>25</volume><issue>3</issue><fpage>40</fpage><lpage>46</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Галлямутдинов Р.В., Головнева Е.С., Ревель-Муроз Ж.А., Еловских И.В., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Галлямутдинов Р.В., Головнева Е.С., Ревель-Муроз Ж.А., Еловских И.В.</copyright-holder><copyright-holder xml:lang="en">Gallyamutdinov R.V., Golovneva E.S., Revel-Muroz Z.A., Elovsky I.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://goslasmed.elpub.ru/jour/article/view/737">https://goslasmed.elpub.ru/jour/article/view/737</self-uri><abstract><p>Лазерное воздействие стимулирует пролиферацию клеток и восстановление тканей. Аминокислоты с разветвленной боковой цепью (BCAA) широко применяются в спортивной медицине как стимулятор анаболических процессов. Однако отсутствуют данные о влиянии комбинированного применения лазера и BCAA на морфометрические характеристики мышц при физической нагрузке в тренировочном процессе.</p><sec><title>Цель</title><p>Цель: изучение влияния инфракрасного лазерного воздействия в комбинации с приемом аминокислот на миосателлитоциты и миоциты скелетной мышцы при тренировках плаванием.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Эксперимент проведен на 30 крысах Вистар: 1-я группа – интактные; 2-я – динамический контроль (тренировки принудительным плаванием); 3-я группа – тренировки и BCAA; 4-я группа – тренировки и лазерное воздействие на мышцы бедра (970 нм, 1 Вт, 60 с); 5-я группа – тренировки, воздействие лазера в комбинации с ВСАА. Тренировки осуществлялись трижды в неделю, 6 недель, лазерное воздействие проводилось после каждой тренировки. Образцы двуглавой мышцы бедра фиксировали формалином, готовили гистологические срезы, окрашенные гематоксилином-эозином. Проводился морфометрический анализ цифрового изображения объектов со статистической обработкой методом Манна – Уитни.</p></sec><sec><title>Результаты</title><p>Результаты. Применение лазерного воздействия комбинированного с BCAA при тренировках приводило к увеличению площади ядер и количества миосателлитов и миоцитов, увеличению поперечного сечения мышечных волокон, более выраженным по сравнению с изолированным лазерным облучением мышцы или приемом ВСАА.</p></sec><sec><title>Заключение</title><p>Заключение. Инфракрасное лазерное воздействие в комбинации с приемом аминокислот с разветвленной боковой цепью эффективно стимулирует регенерацию путем гиперплазии и гипертрофии скелетной мышечной ткани, что обеспечивает физиологическую адаптацию при тренировочном процессе.</p></sec></abstract><trans-abstract xml:lang="en"><p>Laser exposure stimulates cell proliferation and tissue repair. Branched-chain amino acids (BCAA) are widely used in sports medicine as a stimulator of anabolic processes. However, there is no evidence of the effect of combined laser and BCAA application on skeletal muscle morphometric characteristics during exercise in the training process.</p><sec><title>Purpose</title><p>Purpose: to study the effect of infrared laser exposure in combination with amino acid at myosatellitocytes and skeletal muscle myocytes during swimming training.</p></sec><sec><title>Material and methods</title><p>Material and methods. The experiment was conducted on 30 Wistar rats: Group 1 – intact, Group 2 – dynamic control (trainings with endurance swimming), Group 3 – trainings and BCAA, Group 4 – trainings and laser exposure at hip muscles (970 nm, 1 W, 60 s), Group 5 – combined exposure to laser and BCAA. Trainings were three times a week for 6 weeks; laser session was after each training. Samples of the bipedal thigh muscle were ﬁxed with formalin; histological sections were stained with hematoxylin-eosin. The morphometric analysis of the digital image of objects with statistical processing by Mann – Whitney method was made.</p></sec><sec><title>Results</title><p>Results. Laser exposure combined with BCAA during trainings increased the nuclei area and the number of myosatellites and myocytes; it also enlarged the cross section of muscle ﬁbers which was more pronounced if to compare with isolated laser irradiation of the muscle or BCAA.</p></sec><sec><title>Conclusions</title><p>Conclusions. Infrared laser exposure in combination with branched-chain amino acids effectively stimulates regeneration due to hyperplasia and hypertrophy of skeletal muscular tissue, thus providing physiological adaptation in the training process.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>лазер</kwd><kwd>ВСАА</kwd><kwd>скелетные мышцы</kwd><kwd>миосателлиты</kwd><kwd>миоциты</kwd><kwd>тренировка</kwd></kwd-group><kwd-group xml:lang="en"><kwd>laser</kwd><kwd>BCAA</kwd><kwd>skeletal muscles</kwd><kwd>myosatellitocytes</kwd><kwd>myocytes</kwd><kwd>training</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ahtiainen J.P. Physiological and molecular adaptations to strength training. In: Concurrent Aerobic and Strength Training. Springer, Cham; 2019: 51–73. DOI: 10.1007/978-3319-75547-2_5</mixed-citation><mixed-citation xml:lang="en">Ahtiainen J.P. 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