<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">goslasmed</journal-id><journal-title-group><journal-title xml:lang="ru">Лазерная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Laser Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8004</issn><issn pub-type="epub">2686-8644</issn><publisher><publisher-name>Skobelkin Centre for Laser Medicine - a branch of the Federal Clinical Center for High Medical Technologies, FMBA of Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37895/2071-8004-2019-23-4-28-37</article-id><article-id custom-type="elpub" pub-id-type="custom">goslasmed-488</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>Предикторы рецидивов базальноклеточного рака кожи после проведения фотодинамической терапии с фотосенсибилизатором фотолон</article-title><trans-title-group xml:lang="en"><trans-title>Predictors of basal cell skin cancer recurrences after photodynamic therapy with Photolon photosensitizer</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Капинус</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kapinus</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">kapinus70@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каплан</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaplan</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сокол</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokol</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ярославцева-Исаева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yaroslavtseva-Isayeva</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Спиченкова</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Spichenkova</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каприн</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaprin</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Медицинский радиологический научный центр имени А.Ф. Цыба филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">A. Tsyb Medical Radiological Research Center<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>06</day><month>03</month><year>2020</year></pub-date><volume>23</volume><issue>4</issue><fpage>28</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Капинус В.Н., Каплан М.А., Сокол Н.И., Ярославцева-Исаева Е.В., Спиченкова И.С., Каприн А.Д., Иванов С.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Капинус В.Н., Каплан М.А., Сокол Н.И., Ярославцева-Исаева Е.В., Спиченкова И.С., Каприн А.Д., Иванов С.А.</copyright-holder><copyright-holder xml:lang="en">Kapinus V.N., Kaplan M.A., Sokol N.I., Yaroslavtseva-Isayeva E.V., Spichenkova I.S., Kaprin A.D., Ivanov S.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://goslasmed.elpub.ru/jour/article/view/488">https://goslasmed.elpub.ru/jour/article/view/488</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>фотодинамическая терапия</kwd><kwd>фотосенсибилизатор фотолон</kwd><kwd>базальноклеточный рак кожи</kwd><kwd>рецидив опухоли</kwd><kwd>предиктор рецидива</kwd></kwd-group><kwd-group xml:lang="en"><kwd>photodynamic therapy</kwd><kwd>Photolon photosensitizer</kwd><kwd>basal cell skin cancer</kwd><kwd>tumor recurrence</kwd><kwd>recurrence predictor</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Барышев В.П. Опыт амбулатоpной хиpуpгии базальноклеточного pака // Российский онкологический журнал. – 2001. – № 4. – С. 41–49.</mixed-citation><mixed-citation xml:lang="en">Baryshev V.P. Outpatient surgery of basal cell carcinoma. Rossiysky oncologichesky zhurnal. 2001; 4: 41–49. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Волгин В.Н., Странадко Е.Ф., Тришкина О.В. и др. Сравнительная характеристика различных видов лечения базальноклеточного рака кожи // Российский журнал кожных и венерических болезней. – 2013. – № 5. – С. 4–10.</mixed-citation><mixed-citation xml:lang="en">Volgin V.N., Stranadko E.Ph., Trishkina O.V. et al. Comparative characteristics of various types of treatment for basal cell skin cancer. Rossiyskiy zhurnal kozhnykh i venericheskikh bolezney. 2013; 5: 4–10. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Дубенский В.В., Гармонов А.А. Современные аспекты эпидемиологии, патогенеза, клиники и лечения базальноклеточного рака кожи // Вестник дерматологии и венерологии. – 2004. – № 6. – С. 7–12.</mixed-citation><mixed-citation xml:lang="en">Dubensky V.V., Garmonov A.A. Modern aspects of epidemiology, pathogenesis, clinics and treatment of basal cell skin cancer. Vestnik dermatologii i venerologii. 2004; 6: 7–12. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Дубенский В.В. Новообразования кожи в практике дерматовенеролога. Вопросы эпидемиологии, этиологии и патогенеза, диагностики // Вестник дерматологии и венерологии. – 2008. – № 6. – С. 22–40.</mixed-citation><mixed-citation xml:lang="en">Dubensky V.V. Skin neoplasms in the practice of a dermatovenerologist. Issues of epidemiology, etiology and pathogenesis, diagnostics. Vestnik dermatologii i venerologii. 2008; 6: 22–40. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Каприн А.Д., Старинский В.В., Петрова Г.В. (ред.) Злокачественные новообразования в России в 2015 г. – М.: МНИОИ им. П.А. Герцена, 2017. – 250 с.</mixed-citation><mixed-citation xml:lang="en">Kaprin A.D., Starinsky V.V., Petrova G.V. (Ed.) Malignant neoplasms in Russia in 2015. M., Herzen Oncological Institute, 2017: 250. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Кацамбас А.Д., Лотти Т.М. Европейское руководство по лечению дерматологических болезней. – М.: Медпресс-информ, 2008. – 727 с.</mixed-citation><mixed-citation xml:lang="en">Katsambas A.D., Lotti T.M. European guidelines for the treatment of dermatological diseases. M.: Medpress-inform, 2008: 727. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Кондратьева Е.Г., Ламоткин И.А. Эффективность лечения базальноклеточного рака кожи. Тез. докл. Всерос. науч.практ. конф.: Актуальные проблемы оказания специализированной медицинской помощи в условиях стационара и применение стационарозамещающих технологий. – М., 2009. – С. 18.</mixed-citation><mixed-citation xml:lang="en">Kondratyev E.G., Lamotkin I.A. Effectiveness of treatment of basal cell skin cancer. Conference Proceedings: Actual problems of providing specialized medical care in a hospital setting and hospital-replacing technologies. M., 2009: 18. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Кунте К., Конц В. Современные рекомендации по терапии базальноклеточной и плоскоклеточной карцином // Дерматология. – 2012. – № 3. – С. 179–186.</mixed-citation><mixed-citation xml:lang="en">Kunte K., Konz V. Modern recommendations for the treatment of basal cell and squamous cell carcinomas. Dermatologia. 2012; 3: 179–186. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Молочков В.А., Снарская Е.С., Поляков П.Ю. и др. К проблеме лечения базалиом кожи // Российский журнал кожных и венерических болезней. – 2005. – № 6. – С. 4–9.</mixed-citation><mixed-citation xml:lang="en">Molochkov V.A., Snarskaya E.S., Polyakov P.Yu. et al. On the problem of treatment of skin basalomas. Rossiyskiy zhurnal kozhnykh i venericheskikh bolezney. 2005; 6: 4–9. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Рябов М.В., Странадко Е.Ф., Волкова Н.Н. Фотодинамическая терапия местно-распространенного базальноклеточного рака кожи // Лазерная медицина. – 2004. – Т. 4. – Вып. 1. С. 18–24.</mixed-citation><mixed-citation xml:lang="en">Ryabov M.V., Stranadko E.F., Volkova N.N. Photodynamic therapy of locally advanced basal cell skin cancer. Lasernaya medicina. 2004; 4 (1): 18–24. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Снарская Е.С. Лечение базальноклеточного рака кожи внутритканевым введением препаратов интерферона // Российский журнал кожных и венерических болезней. – 2005. – № 1. С. 8–16.</mixed-citation><mixed-citation xml:lang="en">Snarskaya E.S. Treatment of basal cell skin cancer with interstitial administration of interferon preparations. Rossiyskiy zhurnal kozhnykh i venericheskikh bolezney. 2005; 1: 8–16. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Снарская Е.С., Молочков В.А. Базалиома. – М.: Медицина, 2003. – 136 с.</mixed-citation><mixed-citation xml:lang="en">Snarskaya E.S., Molochkov V.A. Basalioma. M.: Medicine, 2003: 136. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Странадко Е.Ф., Волгин В.Н., Ламоткин И.А., Рябов М.В. Фотодинамическая терапия базальноклеточного рака кожи с фотосенсибилизатором второго поколения фосканом // Российские медицинские вести. – 2009. – Т. 14. – № 1. С. 62–68.</mixed-citation><mixed-citation xml:lang="en">Stranadko E.F., Volgin V.N., Lamotkin I.A., Ryabov M.V. Photodynamic therapy of basal cell skin cancer with a second-generation photosensitizer Phoscan. Rossiyskiye meditsinskiye vesti. 2009; 14 (1): 62–68. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Странадко Е.Ф., Рябов М.В. Двадцатилетний опыт фотодинамической терапии рака кожи // Лазерная медицина. – 2012. Т. 16. – Вып. 2. – С. 19–25.</mixed-citation><mixed-citation xml:lang="en">Stranadko E.F., Ryabov M.V. Twenty Years of Photodynamic Therapy for Skin Cancer. Lasernaya medicina. 2012; 16 (2): 19–25. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Сухова Т.Е. Противоопухолевое действие фотодинамической терапии в эксперименте и при базальноклеточном раке кожи: Автореф. дис. ... д-ра мед. наук. – М., 2012. – 48 с.</mixed-citation><mixed-citation xml:lang="en">Sukhova T.E. Antitumor effect of photodynamic therapy in an experiment and in basal cell skin cancer: Abstract of Doctorate dissertation. M., 2012: 48. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Сучков С.В., Молочков В.А., Снарская Е.С. Современные программы лечебно-реабилитационных мероприятий при базалиомах: патогенетическое обоснование и клиническая эффективность // Российский журнал кожных и венерических болезней. – 2007. – № 5. – С. 24–28.</mixed-citation><mixed-citation xml:lang="en">Suchkov S.V., Molochkov V.A., Snarskaya E.S. Modern programs of treatment and rehabilitation measures for basal cell carcinomas: pathogenetic substantiation and clinical effectiveness. Rossiyskiy zhurnal kozhnykh i venericheskikh bolezney. 2007; 5: 24–28. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Филоненко Е.В. Физические методы в лечении больных раком кожи // Медицинские технологии. Оценка и выбор. – 2012. – № 2. – С. 100–105.</mixed-citation><mixed-citation xml:lang="en">Filonenko E.V. Physical methods in the treatment of skin cancer patients. Medical technology. Rating and selection. 2012; 2: 100–105. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Basset-Seguin N., Ibbotson S.H., Emtestam L. et al. Topical methyl aminolaevulinate photodynamic therapy versus cryotherapy for superﬁcial basal cell carcinoma: a 5 year randomized trial. European Journal of Dermatology. 2008; 18 (5): 547–553.</mixed-citation><mixed-citation xml:lang="en">Basset-Seguin N., Ibbotson S.H., Emtestam L. et al. Topical methyl aminolaevulinate photodynamic therapy versus cryotherapy for superﬁcial basal cell carcinoma: a 5 year randomized trial. European Journal of Dermatology. 2008; 18 (5): 547–553.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Bath-Hextall F.J., Perkins W., Bong J., Williams H.C. Interventions for basall cell carcinoma of the skin. Cochrane Database Syst. Rev. 2007; 1: CD003412.</mixed-citation><mixed-citation xml:lang="en">Bath-Hextall F.J., Perkins W., Bong J., Williams H.C. Interventions for basall cell carcinoma of the skin. Cochrane Database Syst. Rev. 2007; 1: CD003412.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Berking C., Hauschild A., Kölbl O. et al. Basal Cell Carcinoma Treatments for the Commonest Skin Cancer. Dtsch. Arzteblatt Int. 2014; 111: 389–395.</mixed-citation><mixed-citation xml:lang="en">Berking C., Hauschild A., Kölbl O. et al. Basal Cell Carcinoma Treatments for the Commonest Skin Cancer. Dtsch. Arzteblatt Int. 2014; 111: 389–395.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Bower C.P., Lear J.T., de Berker D.A. Basal cell carcinoma followup practices by dermatologists: a national survey. Br. J. Dermatol. 2001; 145 (6): 949–956.</mixed-citation><mixed-citation xml:lang="en">Bower C.P., Lear J.T., de Berker D.A. Basal cell carcinoma followup practices by dermatologists: a national survey. Br. J. Dermatol. 2001; 145 (6): 949–956.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Cosgarea R., Susan M., Crisan M., Senila S. Photodynamic therapy using topical 5-aminolaevulinic acid vs surgery for basal cell carcinoma. J. Eur. Acad. Dermatol. Venereol. 2013; 27 (8): 980–984.</mixed-citation><mixed-citation xml:lang="en">Cosgarea R., Susan M., Crisan M., Senila S. Photodynamic therapy using topical 5-aminolaevulinic acid vs surgery for basal cell carcinoma. J. Eur. Acad. Dermatol. Venereol. 2013; 27 (8): 980–984.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Fantini F., Greco A., Del Giovane C. et al. Photodynamic therapy for basal cell carcinoma: clinical and pathological determinants of response. J. Eur. Acad. Dermatol. Venereol. 2011; 25 (8): 896–901.</mixed-citation><mixed-citation xml:lang="en">Fantini F., Greco A., Del Giovane C. et al. Photodynamic therapy for basal cell carcinoma: clinical and pathological determinants of response. J. Eur. Acad. Dermatol. Venereol. 2011; 25 (8): 896–901.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Lai S.Y., Weber R.S. High-risk non-melanoma skin cancer of the head and neck. Curr. Oncol. Rep USA. 2005; 7 (2): 154–158.</mixed-citation><mixed-citation xml:lang="en">Lai S.Y., Weber R.S. High-risk non-melanoma skin cancer of the head and neck. Curr. Oncol. Rep USA. 2005; 7 (2): 154–158.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Lebwohl M., Heyman W.R., Berth-Jones J., Coulson J., eds. Treatment of skin disease. Comprehensive therapeutic strategies. Mosby, 2002: 199–211.</mixed-citation><mixed-citation xml:lang="en">Lebwohl M., Heyman W.R., Berth-Jones J., Coulson J., eds. Treatment of skin disease. Comprehensive therapeutic strategies. Mosby, 2002: 199–211.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Liezel L. Grifﬁn and John T. Lear. Photodynamic Therapy and Non-Melanoma Skin CancerCancers. 2016; 8 (10): 98; doi: 10.3390/cancers8100098.</mixed-citation><mixed-citation xml:lang="en">Liezel L. Grifﬁn and John T. Lear. Photodynamic Therapy and Non-Melanoma Skin Cancer. Cancers. 2016; 8 (10): 98; doi: 10.3390/cancers8100098.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Lomas A., Leonardi-Bee J., Bath-Hextall F. A systematic review of worldwide incidence of nonmelanoma skin cancer. Br. J. Dermatol. 2012; 166: 1069–1080.</mixed-citation><mixed-citation xml:lang="en">Lomas A., Leonardi-Bee J., Bath-Hextall F. A systematic review of worldwide incidence of nonmelanoma skin cancer. Br. J. Dermatol. 2012; 166: 1069–1080.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Luz F.B., Ferron C., Cardoso G.P. Surgicaltreatment of basal cell carcinoma: an algorithm based on the literature. An. Bras. Dermatol. 2015; 90 (3): 377–383.</mixed-citation><mixed-citation xml:lang="en">Luz F.B., Ferron C., Cardoso G.P. Surgical treatment of basal cell carcinoma: an algorithm based on the literature. An. Bras. Dermatol. 2015; 90 (3): 377–383.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Mosterd K., Krekels G.A., Nieman F.H. et al. Surgical excision versus Mohs’ micrographic surgery for primary and recurrent basal-cell carcinoma of the face: a prospective randomised controlled trial with 5-years’ follow-up. Lancet Oncol. 2008; 9 (12): 1149–1156.</mixed-citation><mixed-citation xml:lang="en">Mosterd K., Krekels G.A., Nieman F.H. et al. Surgical excision versus Mohs’ micrographic surgery for primary and recurrent basal-cell carcinoma of the face: a prospective randomised controlled trial with 5-years’ follow-up. Lancet Oncol. 2008; 9 (12): 1149–1156.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Rhodes L.E., de Rie M.A., Leifsdottir R. et al. Five year followup of a randomized, prospective trial of methyl aminolevulinate photodynamic therapy vs surgery for nodular basal cell carcinoma. Arch. Dermatol. 2007; 143: 1131–1136.</mixed-citation><mixed-citation xml:lang="en">Rhodes L.E., de Rie M.A., Leifsdottir R. et al. Five year followup of a randomized, prospective trial of methyl aminolevulinate photodynamic therapy vs surgery for nodular basal cell carcinoma. Arch. Dermatol. 2007; 143: 1131–1136.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Roozeboom M.H., Arits A.H., Nelemans P.J., Kelleners-Smeets N.W. Overall treatment success after treatment of primary superﬁcial basal cell carcinoma: a systematic review and meta-analysis of randomized and nonrandomized trials. Br. J. Dermatol. 2012; 167 (4): 733–756.</mixed-citation><mixed-citation xml:lang="en">Roozeboom M.H., Arits A.H., Nelemans P.J., KellenersSmeets N.W. Overall treatment success after treatment of primary superﬁcial basal cell carcinoma: a systematic review and metaanalysis of randomized and nonrandomized trials. Br. J. Dermatol. 2012; 167 (4): 733–756.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Ross A.S., Schmults C.D. Sentinel lymph node biopsy in cutaneous squamous cell carcinoma: a systematic review of the English literature. Dermatol. Surg. 2006; 32 (11): 1309–1321.</mixed-citation><mixed-citation xml:lang="en">Ross A.S., Schmults C.D. Sentinel lymph node biopsy in cutaneous squamous cell carcinoma: a systematic review of the English literature. Dermatol. Surg. 2006; 32 (11): 1309–1321.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Rowe D.E., Carroll R.J., Day C.L., Jr. Long-term recurrence rates in previously untreated (primary) basal cell carcinoma: implications for patient follow-up. J. Dermatol. Surg. Oncol. 1989; 15: 315–328.</mixed-citation><mixed-citation xml:lang="en">Rowe D.E., Carroll R.J., Day C.L., Jr. Long-term recurrence rates in previously untreated (primary) basal cell carcinoma: implications for patient follow-up. J. Dermatol. Surg. Oncol. 1989; 15: 315–328.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Rowe D.E., Carroll R.J., Day C.L., Jr. Prognostic factors for local recurrence, metastasis, and survival rates in squamous cell carcinoma of the skin, ear, and lip. Implications for treatment modality selection. J. Am. Acad. Dermatol. 1992; 26: 976–990.</mixed-citation><mixed-citation xml:lang="en">Rowe D.E., Carroll R.J., Day C.L., Jr. Prognostic factors for local recurrence, metastasis, and survival rates in squamous cell carcinoma of the skin, ear, and lip. Implications for treatment modality selection. J. Am. Acad. Dermatol. 1992; 26: 976–990.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Schulte K.W., Lippold A., Auras C. et al. Soft X-ray therapy for cutaneous basal cell and squamous cell carcinomas. J. Am. Acad. Dermatol. 2005; 53: 993–1001.</mixed-citation><mixed-citation xml:lang="en">Schulte K.W., Lippold A., Auras C. et al. Soft X-ray therapy for cutaneous basal cell and squamous cell carcinomas. J. Am. Acad. Dermatol. 2005; 53: 993–1001.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Sherry K.R., Reid L.A., Wilmshurst A.D. A ﬁve year review of basal cell carcinoma excisions. J. Plast. Reconstr. Aesthet. Surg. 2010; 63 (9): 1485–1489.</mixed-citation><mixed-citation xml:lang="en">Sherry K.R., Reid L.A., Wilmshurst A.D. A ﬁve year review of basal cell carcinoma excisions. J. Plast. Reconstr. Aesthet. Surg. 2010; 63 (9): 1485–1489.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Silva J.J., Tsang R.W., Panzarella T. et al. Results of radiotherapy for epithelial skin cancer of the pinna: the Princess Margaret Hospital experience, 1982–1993. Int. J. Radiat. Oncol. Biol. Phys. 2000; 47: 451–459.</mixed-citation><mixed-citation xml:lang="en">Silva J.J., Tsang R.W., Panzarella T. et al. Results of radiotherapy for epithelial skin cancer of the pinna: the Princess Margaret Hospital experience, 1982–1993. Int. J. Radiat. Oncol. Biol. Phys. 2000; 47: 451–459.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Skiveren J., Mikkelsen M.R., Daugbjerg H., Wulf H.C. Skin reactions and quality of life after x-ray therapy of basal cell carcinoma. J. Skin Cancer. 2012.</mixed-citation><mixed-citation xml:lang="en">Skiveren J., Mikkelsen M.R., Daugbjerg H., Wulf H.C. Skin reactions and quality of life after x-ray therapy of basal cell carcinoma. J. Skin Cancer. 2012.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Ting Lv., Zu-Fang Huang, Hong-Wei Wang et al. Photodiagnosis and photodynamic therapy. 2012; 9 (2): 164–169.</mixed-citation><mixed-citation xml:lang="en">Ting Lv., Zu-Fang Huang, Hong-Wei Wang et al. Photodiagnosis and photodynamic therapy. 2012; 9 (2): 164–169.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Tsao M.N., Tsang R.W., Liu F.F. et al. Radiotherapy management for squamous cell carcinoma of the nasal skin: the Princess Margaret Hospital experience. Int. J. Radiat. Oncol. Biol. Phys. 2002; 52: 973–979.</mixed-citation><mixed-citation xml:lang="en">Tsao M.N., Tsang R.W., Liu F.F. et al. Radiotherapy management for squamous cell carcinoma of the nasal skin: the Princess Margaret Hospital experience. Int. J. Radiat. Oncol. Biol. Phys. 2002; 52: 973–979.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Vinciullo C., Elliott T., Francis D. et al. Photodynamic therapy with topical methyl aminolaevulinate for “difﬁcult-to-treat” basal cell carcinoma. Br. J. Dermatol. 2005; 152: 765–772.</mixed-citation><mixed-citation xml:lang="en">Vinciullo C., Elliott T., Francis D. et al. Photodynamic therapy with topical methyl aminolaevulinate for “difﬁcult-to-treat” basal cell carcinoma. Br. J. Dermatol. 2005; 152: 765–772.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Zagrodnik B., Kempf W., Seifert B. et al. Superﬁcial radiotherapy for patients with basal cell carcinoma: recurrence rates, histologic subtypes, and expression of p53 and Bcl-2. Cancer. 2003; 98: 2708–2714.</mixed-citation><mixed-citation xml:lang="en">Zagrodnik B., Kempf W., Seifert B. et al. Superﬁcial radiotherapy for patients with basal cell carcinoma: recurrence rates, histologic subtypes, and expression of p53 and Bcl-2. Cancer. 2003; 98: 2708–2714.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
