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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">goslasmed</journal-id><journal-title-group><journal-title xml:lang="ru">Лазерная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Laser Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8004</issn><issn pub-type="epub">2686-8644</issn><publisher><publisher-name>Skobelkin Centre for Laser Medicine - a branch of the Federal Clinical Center for High Medical Technologies, FMBA of Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37895/2071-8004-2019-23-2-37-43</article-id><article-id custom-type="elpub" pub-id-type="custom">goslasmed-466</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>Влияние лазерного излучения на взаимодействие капроновых нитей с тканями ран (экспериментальное исследование)</article-title><trans-title-group xml:lang="en"><trans-title>Laser light effects at the interaction of nylon threads with wound tissues</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Байбеков</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Baybekov</surname><given-names>I. M.</given-names></name></name-alternatives><email xlink:type="simple">baibekov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бутаев</surname><given-names>А. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Butaev</surname><given-names>A. Kh.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мардонов</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Mardonov</surname><given-names>D. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ГУ «Республиканский специализированный научно-практический медицинский центр хирургии им акад. В. Вахидова»<country>Узбекистан</country></aff><aff xml:lang="en">Republican Specialized Scientific and Practical Medical Center of Surgery named after Akad. Vakhidov<country>Uzbekistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>09</day><month>11</month><year>2019</year></pub-date><volume>23</volume><issue>2</issue><fpage>37</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Байбеков И.М., Бутаев А.Х., Мардонов Д.Н., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Байбеков И.М., Бутаев А.Х., Мардонов Д.Н.</copyright-holder><copyright-holder xml:lang="en">Baybekov I.M., Butaev A.K., Mardonov D.N.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://goslasmed.elpub.ru/jour/article/view/466">https://goslasmed.elpub.ru/jour/article/view/466</self-uri><abstract><p>Цель: исследовать влияние низкоинтенсивного лазерного излучения (НИЛИ) на заживление кожных ран и взаимодействие моно- и полифиламентных капроновых нитей с биотканями. Материал и методы. Линейные раны воспроизводили в области спины белых крыс, разделенных на следующие группы: основная группа – 28 животных, подвергнутых лазерному воздействию; контрольная группа – 24 крысы, которые не подвергались лазерному воздействию, а также 6 интактных крыс (норма). Раны облучали лазером «Матрикс-ВЛОК» с головкой «КЛ-ВЛОК», длина волны 0,63 мкм, выходная мощность 2 мВт. Для оценки изменений ран и взаимодействия биотканей с нитями капрона использованы методы морфологии, для оценки микроциркуляции ран – лазерная допплеровская флоуметрия аппаратами ЛАКК-01 или АЛТ-Восток, ЛДФ-01 с одноканальными анализаторами, которые сопряжены с компьютером. Проводили оценку соотношения нормальных и патологических форм эритроцитов в ранах. Результаты. Установлено, что полифиламентные нити вызывают более выраженную воспалительную реакцию тканей. НИЛИ снижает проявления воспалительных изменений тканей при контакте с капроновыми нитями, способствует нормализации соотношения нормальных и патологических форм эритроцитов, интенсифицирует микроциркуляцию и способствует ускорению заживления ран. Заключение. Проведенные исследования указывают на эффективность лазерного излучения для уменьшения воспаления и ускорения заживления ран, ушитых капроном.</p></abstract><trans-abstract xml:lang="en"><p>Purpose: to study effects of low-level laser irradiation (LLLI) at the healing process in skin wounds and at the interaction of monofilament and polyfilament nylon threads with biological tissues. Material and methods. Linear wounds were made on the back of white rats. Animals were divided into the following groups: main group – 28 animals subjected to laser irradiation; control group – 24 rats not exposed to laser irradiation; 6 intact rats (normal). Wounds were irradiated with laser Matrix-VLOK with KL-VLOK head, wavelength 0.63 μm, output power 2 mW. Morphological examination assessed changes in wounds and interaction of biotissue with nylon threads. Laser Doppler flowmetry was used for assessing wound microcirculation with devices LAKK-01 or ALT-Vostok and LDF-01 with single-channel analyzers attached to the computer. The ratio of normal and pathological forms of erythrocytes in wounds was analyzed. Results. Polyfilament threads have been found to cause more pronounced inflammatory tissue reactions. LLLI decreases inflammatory changes in tissues which contact nylon threads; it also normalizes the ratio of normal and pathological forms of erythrocytes, intensifies microcirculation and accelerates wound healing. Conclusion. Laser irradiation has been found effective in decreasing inflammation and in accelerating healing process in wounds which are sutured with nylon threads.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>раны</kwd><kwd>капроновые нити</kwd><kwd>лазерное воздействие</kwd><kwd>эритроциты</kwd><kwd>микроциркуляция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>wounds</kwd><kwd>nylon threads</kwd><kwd>laser effects</kwd><kwd>erythrocytes</kwd><kwd>microcirculation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Байбеков И.М., Назыров Ф.Г., Ильхамов Ф.А. и др. Морфологические аспекты лазерных воздействий (на хронические язвы и печень). – Ташкент: Изд-во мед. лит. им. Абу Али ибн Сино, 1996. – 208 с.</mixed-citation><mixed-citation xml:lang="en">Baybekov I.M., Nazyrov F.G., Ilkhamov F.A. et al. Morphological aspects of laser effects (on chronic ulcers and liver) Published by Abu Ali Ibn Sina Medical Literature Publishing House. 1996: 208. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Байбеков И.М., Мавлян-Ходжаев Р.Ш., Эрстекис А.Г., Москвин С.В. Эритроциты в норме, патологии и при лазерных воздействиях. Тверь: Триада, 2008. – 256 с.</mixed-citation><mixed-citation xml:lang="en">Baybekov I.M., Mavlyan-Khojaev R. Sh., Erstekis A.G., Moskvin S.V. Erythrocytes in norm, pathology and under laser influence. Tver: Publishing House «Triada», 2008: 256. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Байбеков И.М., Ибрагимов А.Ф., Байбеков А.И. Влияние лазерного облучения донорской крови на форму эритроцитов // Бюллетень экспериментальной биологии и медицины. – 2011. – Т. 152. – № 12. – С. 703–706.</mixed-citation><mixed-citation xml:lang="en">Baybekov I.M., Ibragimov A.F., Baybekov A.I. Effects of laser irradiation of donor blood at erythrocyte form. Bulleten experimentalnoy biologii i medicini. 2011; 152 (12): 703–706. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Байбеков И.М. Ибрагимов А.Ф., Байбек-Палмос М.И. Лазерные воздействия на кожу и эритроциты в норме и патологии. Саарбрюккен: Lambert. – 2014. – 272 с.</mixed-citation><mixed-citation xml:lang="en">Baybekov I.M. Ibragimov A.F., Baybek-Palmos M.I. Laser effects at skin and red blood cells in healthy and diseased states. Saardrucken: Lambert, 2014: 272. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Байбеков И.М., Бутаев А.Х., Мардонов Д.Н. Влияние лазерного излучения на взаимодействие нитей Этибонда с тканями ран и их заживление //Лазерная медицина. – 2017. – Т. 21. – Вып. 4. – С.11–15.</mixed-citation><mixed-citation xml:lang="en">Baybekov I.M., Butaev A. Kh., Mardonov D.N. Effects of laser irradiation at the interaction of Ethibond threads with wound tissues and healing process. Lasernaya Medicina. 2017; 21 (4): 11–15. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Бонцевич Д.Н. Хирургический шовный материал // Проблемы здоровья и экологии. – 2005. – № 3 (5). – С. 43–48.</mixed-citation><mixed-citation xml:lang="en">Bontsevich D.N. Surgical sutural material. Problemi zdorovia i ekologii. 2005; 3 (5): 43–48. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Брилль Г.Е. Двойственный эффект низкоинтенсивного лазерного излучения на развитие воспалительного процесса // Лазерная медицина. – 2011. – Т. 15. – Вып. 2. – С. 108–109.</mixed-citation><mixed-citation xml:lang="en">Brill G.E. Dual effects of low-level laser irradiation at inflammatory process. Lasernaya Medicina. 2011; 15 (2): 108–109. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Гейниц А.В., Москвин С.В., Азизов Г.А. Внутривенное лазерное облучение крови. – Тверь: Триада, 2006. – 250 с.</mixed-citation><mixed-citation xml:lang="en">Geynitz A.V., Moskvin S.V., Azizov G.A. Intravenous laser blood irradiation. Tver: Triada, 2006: 250. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Гейниц A.B., Цыганова Г.И. ГНЦ лазерной медицины – четверть века на пути создания лазерных инновационных технологий вмедицине // Лазерная медицина. – 2011. – Т. 15. – Вып. 2. – С. 16–18.</mixed-citation><mixed-citation xml:lang="en">Geynitz A.B., Ziganova G.I. Skobelkin State Scientific Center of Laser Medicine – a quarter of century on the way to creating laser innovative technologies in medicine. Lasernaya Medicina. 2011; 15 (2): 16–18. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Елисеенко В.И. Патологическая анатомия и патогенез лазерной раны // Лазерная медицина. – 2017. – Т. 21. – Вып. 4. – С.5–10.</mixed-citation><mixed-citation xml:lang="en">Yeliseenko V.I. Pathologic anatomy and pathogenesis of laser wounds. Lasernaya Medicina. 2017; 21 (4): 5–10. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Елисеенко В.И. 30 лет ФГБУ «ГНЦ лазерной медицины ФМБА России» // Лазерная медицина. – 2016. – Т. 20. – Вып. 3. – С. 114–115.</mixed-citation><mixed-citation xml:lang="en">Yeliseenko V.I. 30 year-anniversary State Research Center of Laser Medicine of the Federal Medical and Biological Agency of Russia. Lasernaya Medicina. 2016; 20 (3): 114–115. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Козлов В.И. Лазерная стимуляция микроциркуляции крови // Современные достижения лазерной медицины и их применение в практическом здравоохранении: материалы научнопрактической конференции 5–6 октября 2006, г. Москва. – М.: Триада, 2006. – С. 174–175.</mixed-citation><mixed-citation xml:lang="en">Kozlov V.I. Laser stimulation of blood microcirculation // Modern achievements of laser medicine and their application in practical healthcare. Proceedings of conference. October 5–6, 2006, Moscow. M.: Triada, 2006: 174–175. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Крупаткин А.И., Сидоров В.В. Лазерная допплеровская флоуметрия микроциркуляции крови. – М.: Медицина, 2005. – 256 с.</mixed-citation><mixed-citation xml:lang="en">Krupatkin A.I., Sidorov V.V. Laser Doppler flowmetry of microcirculation of blood. M.: Medicina, 2005: 256. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Москвин С.В. Основы лазерной терапии. Серия «Эффективная лазерная терапия» Т. 1. – М.–Тверь: Триада, 2016. – 896 с.</mixed-citation><mixed-citation xml:lang="en">Moskvin S.V. Basics of laser therapy. A series of «Effective laser therapy» V. 1. M.–Tver: Triada, 2016: 896. [In Russ.].</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Baybekov I.M., Kartashev V.P., Mardohnov J. Influence of laser irradiation on interaction of prolen sutures with the wound tissues and their healing. Economic and social developmentю Book of Proceedings. – M.: Российский государственный социальный университет, 2017: 15–24.</mixed-citation><mixed-citation xml:lang="en">Baybekov I.M., Kartashev V.P., Mardohnov J. Influence of laser irradiation on interaction of prolen sutures with the wound tissues and their healing. Economic and social developmentю Book of Proceedings. – M.: Russian State Social University, 2017: 15–24.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Hamblin M.R., Ferraresi C., Huang Y., Freitas L. Low-Leve Light Therapy: Photobiomodulation SPIE PRESS. Bellingham, Washington USA, 2018: 367.</mixed-citation><mixed-citation xml:lang="en">Hamblin M.R., Ferraresi C., Huang Y., Freitas L. Low-Leve Light Therapy: Photobiomodulation SPIE PRESS. Bellingham, Washington USA, 2018: 367.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Karakozov P.E., Ibadov B.I., Mardonov J., Baybekov I.M. The Surface of Various Types of Surgical Sutures by Scanning Electron Microscopy. American Journal of Thoracic and Cardiovascular. 2017; 2 (2): 35–40.</mixed-citation><mixed-citation xml:lang="en">Karakozov P.E., Ibadov B.I., Mardonov J., Baybekov I.M. The Surface of Various Types of Surgical Sutures by Scanning Electron Microscopy. American Journal of Thoracic and Cardiovascular. 2017; 2 (2): 35–40.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Ozcelik O., Cenk Haytac M., Kunin A., Seydaoglu G. Improved wound healing by low-level laser irradiation after gingivectomy operations: a controlled clinical pilot study. J. Clin Periodontol. 2008; 35 (3): 250–254.</mixed-citation><mixed-citation xml:lang="en">Ozcelik O., Cenk Haytac M., Kunin A., Seydaoglu G. Improved wound healing by low-level laser irradiation after gingivectomy operations: a controlled clinical pilot study. J. Clin Periodontol. 2008; 35 (3): 250–254.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Photomedicine: Advances in Clinical Practice (Edited by Yohei Tanaka) Published by ExLiEvA Copyright © 2017: 252.</mixed-citation><mixed-citation xml:lang="en">Photomedicine: Advances in Clinical Practice (Edited by Yohei Tanaka) Published by ExLiEvA Copyright © 2017: 252.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Simunovic Z. (Ed-r) Lasers in medicine science and praxis in medicine, surgery, dentistry and veterinary Trilogy updates with emphasis on LILT-photobiostimulation photodynamic therapy and laser acupuncture. Locarno, 2009: 772.</mixed-citation><mixed-citation xml:lang="en">Simunovic Z. (Ed-r) Lasers in medicine science and praxis in medicine, surgery, dentistry and veterinary Trilogy updates with emphasis on LILT-photobiostimulation photodynamic therapy and laser acupuncture. Locarno, 2009: 772.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Tuner J., Hode L. The New Laser Therapy Hand boor Prima book. Stockholm, 2010: 847.</mixed-citation><mixed-citation xml:lang="en">Tuner J., Hode L. The New Laser Therapy Hand boor Prima book. Stockholm, 2010: 847.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Wu C.S., Hu S.C., Lan C.C. et al. Low-energy helium-neon laser therapy induces repigmentation and improves the abnormalities of cutaneous microcirculation in segmental-type vitiligo lesions. Kaohsiung J. Med Sci. 2008; 24 (4): 180–189.</mixed-citation><mixed-citation xml:lang="en">Wu C.S., Hu S.C., Lan C.C. et al. Low-energy helium-neon laser therapy induces repigmentation and improves the abnormalities of cutaneous microcirculation in segmental-type vitiligo lesions. Kaohsiung J. Med Sci. 2008; 24 (4): 180–189.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
