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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">goslasmed</journal-id><journal-title-group><journal-title xml:lang="ru">Лазерная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Laser Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8004</issn><issn pub-type="epub">2686-8644</issn><publisher><publisher-name>Skobelkin Centre for Laser Medicine - a branch of the Federal Clinical Center for High Medical Technologies, FMBA of Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37895/2071-8004-2017-21-2-30-37</article-id><article-id custom-type="elpub" pub-id-type="custom">goslasmed-354</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCHES</subject></subj-group></article-categories><title-group><article-title>Современный взгляд на лечение и профилактику внутриматочных синехий при маточной форме бесплодия</article-title><trans-title-group xml:lang="en"><trans-title>A modern view at the treatment and prophylactics of intrauterous synechias in the uterine form of infertility</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черкасова</surname><given-names>Анастасия Леонидовна</given-names></name><name name-style="western" xml:lang="en"><surname>Cherkassova</surname><given-names>A. L.</given-names></name></name-alternatives><email xlink:type="simple">missdream.88@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Максимова</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Maksimova</surname><given-names>T. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джибладзе</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Djibladze</surname><given-names>T. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зуев</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Zuev</surname><given-names>V. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ищенко</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ischenko</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Брюнин</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Brunin</surname><given-names>D. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хохлова</surname><given-names>И. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Khokhlova</surname><given-names>I. D.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борцвадзе</surname><given-names>Ш. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Bortzvadze</surname><given-names>Sh. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гогоберидзе</surname><given-names>Т. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Gogoberidze</surname><given-names>T. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова»<country>Россия</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">НИИ клинической медицины<country>Россия</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>03</day><month>08</month><year>2018</year></pub-date><volume>21</volume><issue>2</issue><fpage>30</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Черкасова А.Л., Максимова Т.А., Джибладзе Т.А., Зуев В.М., Ищенко А.И., Брюнин Д.В., Хохлова И.Д., Борцвадзе Ш.Н., Гогоберидзе Т.И., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Черкасова А.Л., Максимова Т.А., Джибладзе Т.А., Зуев В.М., Ищенко А.И., Брюнин Д.В., Хохлова И.Д., Борцвадзе Ш.Н., Гогоберидзе Т.И.</copyright-holder><copyright-holder xml:lang="en">Cherkassova A.L., Maksimova T.A., Djibladze T.A., Zuev V.M., Ischenko A.I., Brunin D.V., Khokhlova I.D., Bortzvadze S.N., Gogoberidze T.I.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://goslasmed.elpub.ru/jour/article/view/354">https://goslasmed.elpub.ru/jour/article/view/354</self-uri><abstract><p>Целью данного исследования явилась разработка методов миниинвазивного лечения и профилактики внутриматочных синехий у женщин репродуктивного возраста с маточной формой бесплодия. Исследование проводилось на базе кафедры акушерства и гинекологии № 1 Первого Московского государственного медицинского университета имени И.М. Сеченова. Проводилось обследование и лечение 86 пациенток репродуктивного возраста с внутриматочными синехиями и бесплодием в возрасте от 23 до 45 лет, которые были разделены на 3 группы. Пациенткам первой группы проводили гистероскопию, лазерную деструкцию внутриматочных синехий и введение противоспаечного геля; второй группе женщин проводили гистероскопию и лазерную деструкцию сращений, а третьей группе пациенток проводили инструментальное разрушение синехий при помощи расширителей Гегара и кюретки. В послеоперационном периоде всем пациенткам назначали ангиопротекторную, противовоспалительную и гормональную терапию. При наличии хронического эндометрита назначали антибактериальную терапию, а при выраженном адгезивном процессе - лазерную терапию и физиотерапию. Через 3-6 месяцев после вмешательства проводили контрольную офисную гистероскопию. Всем пациенткам с рецидивом внутриматочных синехий выполнили повторную гистероскопию, лазерную деструкцию внутриматочных синехий и введение противоспаечного геля. Показано, что использование малотравматичных методов лечения и профилактики внутриматочных синехий с применением лазерной хирургии и введением противоспаечного геля пациенткам с маточной формой бесплодия способствовало восстановлению полости матки и наступлению беременности у 52% женщин первой группы, тогда как во второй и третьей группах беременность наступила в 25% и 16,7% соответственно.</p></abstract><trans-abstract xml:lang="en"><p>The aim of the present study was to develop techniques for minim ally invasive treatment and prophylactics of intrauterine synechias in women of the reproductive age having uterine infertility. The work was done at the Department of Obstetrics and Gynecology No. 1 in the First Moscow State Medical University named after Sechenov. 86 patients of reproductive age with intrauterine synechias and infertility aged 23-45 were divided into 3 groups. All patients were examined and treated. Patients from the first group had hysteroscopy, laser destruction of intrauterine synechias and anti-adhesive gel injections; in the second group, women had hysteroscopy and laser destruction of adhesions; in the third group, patients had instrumental destruction of synechias with Hegar's dilators and curettes. In the postoperative period, all patients were prescribed angioprotective, anti-inflammatory and hormone therapy. If patients had a marked adhesive process, they were prescribed laser therapy and physiotherapy. In 3-6 months after the described manipulations, patients had a diagnostic hysteroscopy. All patients with recurrent intrauterine synechias were prescribed a repeated hysteroscopy, laser destruction of intrauterine synechias and anti-adhesive gel injections. As it has been shown, little-traumatic techniques and prophylactics of intrauterine synechias with laser surgery and anti-adhesive gel to patients with uterine infertility helped to restore the uterine cavity with the followed pregnancy in 52% of women from the first group, while in the second and third groups pregnancy developed in 25% and 16.7%, respectively.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>бесплодие</kwd><kwd>лазерная деструкция</kwd><kwd>внутриматочные синехии</kwd><kwd>infertility</kwd><kwd>laser destruction</kwd><kwd>intrauterine synechia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Макаренко Т.А., Никифорова Д.Е. 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