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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">goslasmed</journal-id><journal-title-group><journal-title xml:lang="ru">Лазерная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Laser Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8004</issn><issn pub-type="epub">2686-8644</issn><publisher><publisher-name>Skobelkin Centre for Laser Medicine - a branch of the Federal Clinical Center for High Medical Technologies, FMBA of Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37895/2071-8004-2017-21-1-45-48</article-id><article-id custom-type="elpub" pub-id-type="custom">goslasmed-344</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Возможности виртуальной хромоскопии в эндоскопической диагностике новообразований толстой кишки (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Possibilities of virtual chromoscopy in endoscopic diagnostics of neoplasms in the colon</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дуванский</surname><given-names>Владимир Анатольевич</given-names></name><name name-style="western" xml:lang="en"><surname>Duvansky</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">iva4583@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белков</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Belkov</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБУ «ГНЦ ЛМ ФМБА России»; РУДН<country>Россия</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>03</day><month>08</month><year>2018</year></pub-date><volume>21</volume><issue>1</issue><fpage>45</fpage><lpage>48</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дуванский В.А., Белков А.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Дуванский В.А., Белков А.В.</copyright-holder><copyright-holder xml:lang="en">Duvansky V.A., Belkov A.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://goslasmed.elpub.ru/jour/article/view/344">https://goslasmed.elpub.ru/jour/article/view/344</self-uri><abstract><p>В обзоре литературы проведен анализ современных эндоскопических технологий осмотра толстой кишки. Появление в последние десятилетия дополнительных технологий осмотра, таких как виртуальная хромоскопия, увеличительная эндоскопия, эндосонография, аутофлюоресцентная диагностика, конфокальная лазерная эндомикроскопия, значительно повысили ценность эндоскопических исследований. Приведены результаты оценки эффективности виртуальной хромоскопии в эндоскопической диагностике новообразований толстой кишки. Целью виртуальной хромоскопии является улучшение детализации поверхностных структур, капиллярной сети. Это достижимо за счет применения оптических фильтров и пост-компьютерной обработки изображений. Виртуальная хромоскопия является эффективным методом эндоскопической диагностики новообразований толстой кишки, вместе с тем остается ряд нерешенных вопросов ее применения, что требует дальнейшего ее изучения и совершенствования</p></abstract><trans-abstract xml:lang="en"><p>In the present literature review the authors analyze the state-of-art of modern endoscopic technologies utilized for colon examination. New diagnostic techniques which appeared in last decades -such as virtual chromoscopy, magnifying endoscopy, endosonography, autofluorescent diagnostics, confocal laser endomicroscopy- have significantly increased the importance of endoscopic examinations. In the article, one also can find data which back the effectiveness of virtual chromoendoscopy in endoscopic diagnostics of colon neoplasms. The virtual chromoscopy is aimed to improve a detailed examination of surface structures, capillary network what can be achieved due to optical filters and post-computer image processing. The virtual chromoscopy is an effective technique of endoscopic diagnostics of tumors in the colon. However, there still remains a number of unsolved issues on its application which need further research and perfection.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>колоректальный рак</kwd><kwd>виртуальная хромоскопия</kwd><kwd>эндоскопия</kwd><kwd>colorectal cancer</kwd><kwd>virtual chromoscopy</kwd><kwd>endoscopy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Атлас эндоскопии пищеварительного тракта. Возможности высокого разрешения и изображения в узком спектре / Под ред. Д. Коэн. - М.: Логосфера, 2012. - 343 с.</mixed-citation><mixed-citation xml:lang="en">Атлас эндоскопии пищеварительного тракта. Возможности высокого разрешения и изображения в узком спектре / Под ред. Д. Коэн. - М.: Логосфера, 2012. - 343 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Агейкина Н.В., Дуванский В.А., Князев М.В. Альтернативный путь развития колоректального рака. Эндоскопические и морфологические особенности зубчатых поражений // Эксперим. и клин. гастроэнтерология. - 2013. - № 8. - С. 3-10.</mixed-citation><mixed-citation xml:lang="en">Агейкина Н.В., Дуванский В.А., Князев М.В. Альтернативный путь развития колоректального рака. Эндоскопические и морфологические особенности зубчатых поражений // Эксперим. и клин. гастроэнтерология. - 2013. - № 8. - С. 3-10.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Агейкина Н.В., Дуванский В.А., Князев М.В. и др. Альтернативный путь развития колоректального рака. Г истогенетические и молекулярные особенности зубчатых поражений // Эксперим. и клин. гастроэнтерология. - 2014. - № 7 (107). - С. 4-12.</mixed-citation><mixed-citation xml:lang="en">Агейкина Н.В., Дуванский В.А., Князев М.В. и др. Альтернативный путь развития колоректального рака. Г истогенетические и молекулярные особенности зубчатых поражений // Эксперим. и клин. гастроэнтерология. - 2014. - № 7 (107). - С. 4-12.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Дуванский В.А., Князев М.В., Краев Г.П., Осин В.Л. Эндоскопия в узком спектре и оптическая когерентная томография в диагностике толстокишечных неоплазий // Эндоскопическая хирургия. - 2013. - Т. 1. - С. 206.</mixed-citation><mixed-citation xml:lang="en">Дуванский В.А., Князев М.В., Краев Г.П., Осин В.Л. Эндоскопия в узком спектре и оптическая когерентная томография в диагностике толстокишечных неоплазий // Эндоскопическая хирургия. - 2013. - Т. 1. - С. 206.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Дуванский В.А., Князев М.В., Краев Г.П. Узкоспектральная эндоскопия в визуализации колоректальных неоплазий // Лазерная медицина. - 2014. - Т. 18. - № 4. - С. 73.</mixed-citation><mixed-citation xml:lang="en">Дуванский В.А., Князев М.В., Краев Г.П. Узкоспектральная эндоскопия в визуализации колоректальных неоплазий // Лазерная медицина. - 2014. - Т. 18. - № 4. - С. 73.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Дуванский В.А., Белков А.В., Широкопояс А.С. Технология спектрального цветового выделения в эндоскопической диагностике колоректальных неоплазий // Росс. журнал гастроэнтерологии, гепатологии, колопроктологии. - № 5. - Т. 25. - М., 2015. - С. 114.</mixed-citation><mixed-citation xml:lang="en">Дуванский В.А., Белков А.В., Широкопояс А.С. Технология спектрального цветового выделения в эндоскопической диагностике колоректальных неоплазий // Росс. журнал гастроэнтерологии, гепатологии, колопроктологии. - № 5. - Т. 25. - М., 2015. - С. 114.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Дуванский В.А., Белков А.В. Возможности технологии спектрального цветового выделения в диагностике колоректальных неоплазий // Лазерная медицина. - 2016. - Т. 20. - № 3. - С. 103.</mixed-citation><mixed-citation xml:lang="en">Дуванский В.А., Белков А.В. Возможности технологии спектрального цветового выделения в диагностике колоректальных неоплазий // Лазерная медицина. - 2016. - Т. 20. - № 3. - С. 103.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Князев М.В., Дуванский В.А., Агейкина Н.В. Тримодальная эндоскопия в диагностике заболеваний желудочно-кишечного тракта // Клиническая эндоскопия. - 2012. - Т. 4. - С. 2.</mixed-citation><mixed-citation xml:lang="en">Князев М.В., Дуванский В.А., Агейкина Н.В. Тримодальная эндоскопия в диагностике заболеваний желудочно-кишечного тракта // Клиническая эндоскопия. - 2012. - Т. 4. - С. 2.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Князев М.В., Дуванский В.А. Аутофлуоресцентная эндоскопия в диагностике колоректальных неоплазий // Эндоскопическая хирургия. - 2014. - № 1. - С. 186.</mixed-citation><mixed-citation xml:lang="en">Князев М.В., Дуванский В.А. Аутофлуоресцентная эндоскопия в диагностике колоректальных неоплазий // Эндоскопическая хирургия. - 2014. - № 1. - С. 186.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Князев М.В., Дуванский В.А. Эндоскопическая аутофлуоресценция в визуализации эпителиальных образований толстой кишки // Biomedical Photonics. - 2015. - № S1. - С. 60.</mixed-citation><mixed-citation xml:lang="en">Князев М.В., Дуванский В.А. Эндоскопическая аутофлуоресценция в визуализации эпителиальных образований толстой кишки // Biomedical Photonics. - 2015. - № S1. - С. 60.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Князев М.В. Дуванский В.А. Эндоскопическое лечение гастроинтестинальных неоплазий - эволюция метода // Вестник хирургии им. И.И. Грекова. - 2015. - Т. 174. - № 2. - С. 130-134.</mixed-citation><mixed-citation xml:lang="en">Князев М.В. Дуванский В.А. Эндоскопическое лечение гастроинтестинальных неоплазий - эволюция метода // Вестник хирургии им. И.И. Грекова. - 2015. - Т. 174. - № 2. - С. 130-134.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Шулешова А.Г., Брехов Е.И., Завьялов М.О. и др. Конфокальная лазерная эндомикроскопия в диагностике неоплазий желудка // Эндоскопическая хирургия. - 2014. - № 5. - С. 24-30.</mixed-citation><mixed-citation xml:lang="en">Шулешова А.Г., Брехов Е.И., Завьялов М.О. и др. Конфокальная лазерная эндомикроскопия в диагностике неоплазий желудка // Эндоскопическая хирургия. - 2014. - № 5. - С. 24-30.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Aminalai A., Rösch T., Aschenbeck J. et al. Live image processing does not increase adenoma detection rate during colonoscopy: a</mixed-citation><mixed-citation xml:lang="en">Aminalai A., Rösch T., Aschenbeck J. et al. Live image processing does not increase adenoma detection rate during colonoscopy: a</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Лазерная медицина. - 2017. - Т. 21, вып. 1 Обзоры randomized comparison between FICE and conventional imaging (Berlin colonoscopy project 5, BECOP-5) // Am. J. Gastroenterol. -2010. - 105 (11). - Р. 2383-2388.</mixed-citation><mixed-citation xml:lang="en">Лазерная медицина. - 2017. - Т. 21, вып. 1 Обзоры randomized comparison between FICE and conventional imaging (Berlin colonoscopy project 5, BECOP-5) // Am. J. Gastroenterol. -2010. - 105 (11). - Р. 2383-2388.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">ASGE Technology Committee, Manfredi M.A., Abu Dayyeh B.K., Bhat Y.M. et al. Electronic chromoendoscopy. Gastrointest Endosc. - 2015. - 81D2. - 249 р.</mixed-citation><mixed-citation xml:lang="en">ASGE Technology Committee, Manfredi M.A., Abu Dayyeh B.K., Bhat Y.M. et al. Electronic chromoendoscopy. Gastrointest Endosc. - 2015. - 81D2. - 249 р.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Bartel M.J., Picco M.F., Wallace M.B. et al. Chromocolonoscopy // Gastrointest Endosc. Clin. N. Am. 2015. - 25 (2). - Р. 243-260.</mixed-citation><mixed-citation xml:lang="en">Bartel M.J., Picco M.F., Wallace M.B. et al. Chromocolonoscopy // Gastrointest Endosc. Clin. N. Am. 2015. - 25 (2). - Р. 243-260.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Bowman E.A., Pfau P.R., Mitra A. et al. High definition colonoscopy combined with i-SCAN imaging technology is superior in the detection of adenomas and advanced lesions compared to high definition colonoscopy alone // Diagn. Ther. Endosc. - 2015. - 167406 р.</mixed-citation><mixed-citation xml:lang="en">Bowman E.A., Pfau P.R., Mitra A. et al. High definition colonoscopy combined with i-SCAN imaging technology is superior in the detection of adenomas and advanced lesions compared to high definition colonoscopy alone // Diagn. Ther. Endosc. - 2015. - 167406 р.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Douvansky V.A. Kniazev M. V. Autofluorescent endoscopic diagnostics of epithelial neoplasms in the colon // J. of Gastroenterology and Hepatology. - 2015. - 30 (Suppl. 4). - 211 р.</mixed-citation><mixed-citation xml:lang="en">Douvansky V.A. Kniazev M. V. Autofluorescent endoscopic diagnostics of epithelial neoplasms in the colon // J. of Gastroenterology and Hepatology. - 2015. - 30 (Suppl. 4). - 211 р.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">East J.E., Ignjatovic A., Suzuki N. et al. A randomized, controlled trial of narrow-band imaging vs highdefinition white light for adenoma detection in patients at high risk of adenomas. Color Dis. - 2012. - 14 (11). - Р. e771-e778.</mixed-citation><mixed-citation xml:lang="en">East J.E., Ignjatovic A., Suzuki N. et al. A randomized, controlled trial of narrow-band imaging vs highdefinition white light for adenoma detection in patients at high risk of adenomas. Color Dis. - 2012. - 14 (11). - Р. e771-e778.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Ferlay J., Soerjomataram I., Ervik M. et al. GLOBOCAN 2012 v10, cancer incidence and mortality worldwide: IARC cancer base № 11. - Lyon: International Agency for Research on Cancer, 2013. http://globocan.iarc.fr.</mixed-citation><mixed-citation xml:lang="en">Ferlay J., Soerjomataram I., Ervik M. et al. GLOBOCAN 2012 v10, cancer incidence and mortality worldwide: IARC cancer base № 11. - Lyon: International Agency for Research on Cancer, 2013. http://globocan.iarc.fr.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Guo C.G., Ji R., Li Y.Q. Accuracy of i-Scan for optical diagnosis of colonic polyps: a meta-analysis. PLoS One. - 2015. - 10 (5). -e0126237 р.</mixed-citation><mixed-citation xml:lang="en">Guo C.G., Ji R., Li Y.Q. Accuracy of i-Scan for optical diagnosis of colonic polyps: a meta-analysis. PLoS One. - 2015. - 10 (5). -e0126237 р.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Hewett D.G., Sano Y., Kaltebach T. et al. Validation of a simple classification system for endoscopic diagnosis of small colorectal polyps using narrow band imaging // Gastroenterology. - 2012. -143. - Р. 599-607.</mixed-citation><mixed-citation xml:lang="en">Hewett D.G., Sano Y., Kaltebach T. et al. Validation of a simple classification system for endoscopic diagnosis of small colorectal polyps using narrow band imaging // Gastroenterology. - 2012. -143. - Р. 599-607.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Hoffman A., Loth L., Rey J.W. et al. High definition plus colonoscopy combined with i-scan tone enhancement vs. high definition colonoscopy for colorectal neoplasia: a randomized trial. Dig Liver Dis. - 2014. - 46 (11).- Р. 991-996.</mixed-citation><mixed-citation xml:lang="en">Hoffman A., Loth L., Rey J.W. et al. High definition plus colonoscopy combined with i-scan tone enhancement vs. high definition colonoscopy for colorectal neoplasia: a randomized trial. Dig Liver Dis. - 2014. - 46 (11).- Р. 991-996.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Hofmann A., Sar F., Goetz M. et al. High definition colonoscopy combined with i-Scan is superior in the detection of colorectal neoplasia compared with standard video colonoscopy: a prospective randomized controlled trial // Endoscopy. - 2010. - 42. -Р. 827-833.</mixed-citation><mixed-citation xml:lang="en">Hofmann A., Sar F., Goetz M. et al. High definition colonoscopy combined with i-Scan is superior in the detection of colorectal neoplasia compared with standard video colonoscopy: a prospective randomized controlled trial // Endoscopy. - 2010. - 42. -Р. 827-833.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Hong S.N., Choe W.H., Lee J.H. et al. Prospective, randomized, back-to-back trial evaluating the usefulness of i-SCAN in screening colonoscopy // Gastrointest Endosc. - 2012. - 75 (5). -Р. 1011-1021.</mixed-citation><mixed-citation xml:lang="en">Hong S.N., Choe W.H., Lee J.H. et al. Prospective, randomized, back-to-back trial evaluating the usefulness of i-SCAN in screening colonoscopy // Gastrointest Endosc. - 2012. - 75 (5). -Р. 1011-1021.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Ijspeert J.E., Bastiaansen B.A., van Leerdam M.E. et al. Development and validation of the WASP classification system for optical diagnosis of adenomas, hyperplastic polyps and sessile serrated adenomas/ polyps. Gut. - 2015. - doi: 10.1136/gutjnl-2014-308411.</mixed-citation><mixed-citation xml:lang="en">Ijspeert J.E., Bastiaansen B.A., van Leerdam M.E. et al. Development and validation of the WASP classification system for optical diagnosis of adenomas, hyperplastic polyps and sessile serrated adenomas/ polyps. Gut. - 2015. - doi: 10.1136/gutjnl-2014-308411.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Ikematsu H., Saito Y., Tanaka S. et al. The impact of narrow band imaging for colon polyp detection: a multi-center randomized controlled trial by tandem colonoscopy // J. Gastroenterol. - 2012. - 47 (10). - Р. 1099-1107.</mixed-citation><mixed-citation xml:lang="en">Ikematsu H., Saito Y., Tanaka S. et al. The impact of narrow band imaging for colon polyp detection: a multi-center randomized controlled trial by tandem colonoscopy // J. Gastroenterol. - 2012. - 47 (10). - Р. 1099-1107.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Jin X.F., Chai T.H., Shi J.W. et al. Meta-analysis for evaluating the accuracy of endoscopy with narrow band imaging in detecting colorectal adenomas // J. Gastroenterol. Hepatol. - 2012. -27 (5). - Р. 882-887.</mixed-citation><mixed-citation xml:lang="en">Jin X.F., Chai T.H., Shi J.W. et al. Meta-analysis for evaluating the accuracy of endoscopy with narrow band imaging in detecting colorectal adenomas // J. Gastroenterol. Hepatol. - 2012. -27 (5). - Р. 882-887.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Kniazev M.V., Douvansky V.A. Autofluorescence of the epithelial neoplasia in the stomach / J. of Gastroenterology and Hepatology. - 2013. - Т. 28. - № S3. - С. 718.</mixed-citation><mixed-citation xml:lang="en">Kniazev M.V., Douvansky V.A. Autofluorescence of the epithelial neoplasia in the stomach / J. of Gastroenterology and Hepatology. - 2013. - Т. 28. - № S3. - С. 718.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Kolligs F.T., Crispin A., Graser A. et al. Risk factors for advanced neoplasia with in subcentimetric polyps: implications for diagnostic imaging. Gut. - 2013. - 62. - Р. 863-870.</mixed-citation><mixed-citation xml:lang="en">Kolligs F.T., Crispin A., Graser A. et al. Risk factors for advanced neoplasia with in subcentimetric polyps: implications for diagnostic imaging. Gut. - 2013. - 62. - Р. 863-870.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Leung W.K., Lo O.S., Liu K.S. et al. Detection of colorectal adenoma by narrow band imaging DHQ190] vs. high definition white light colonoscopy: a randomizedcontrolled trial // Am. J. Gastroenterol. - 2014. - 109D6. - Р. 855-863.</mixed-citation><mixed-citation xml:lang="en">Leung W.K., Lo O.S., Liu K.S. et al. Detection of colorectal adenoma by narrow band imaging DHQ190] vs. high definition white light colonoscopy: a randomizedcontrolled trial // Am. J. Gastroenterol. - 2014. - 109D6. - Р. 855-863.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Longcroft-Wheaton G.R.,Higgins B., Bhandari P. Flexible spectral imaging color enhancement and indigo carmine in neoplasia diagnosis during colonoscopy: alarge prospective UK series // Eur. J. Gastroenterol. Hepatol. - 2011. - 23. - Р. 903-911.</mixed-citation><mixed-citation xml:lang="en">Longcroft-Wheaton G.R.,Higgins B., Bhandari P. Flexible spectral imaging color enhancement and indigo carmine in neoplasia diagnosis during colonoscopy: alarge prospective UK series // Eur. J. Gastroenterol. Hepatol. - 2011. - 23. - Р. 903-911.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Omata F., Ohde S., Deshpande G.A. et al. Image-enhanced chromo and cap-assisted colonoscopy for improving adenoma/neoplasia detection rate: a systematic review and meta-analysis // Scand. J. Gastroenterol. -2014. - 49 (2). - Р. 222-237.</mixed-citation><mixed-citation xml:lang="en">Omata F., Ohde S., Deshpande G.A. et al. Image-enhanced chromo and cap-assisted colonoscopy for improving adenoma/neoplasia detection rate: a systematic review and meta-analysis // Scand. J. Gastroenterol. -2014. - 49 (2). - Р. 222-237.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Osawa H., Yamamoto H. Present and future status of flexible spectral imaging color enhancement and blue laser imaging technology // Dig. Endosc. - 2014. - 26 (Suppl. 1). - Р. 105-115.</mixed-citation><mixed-citation xml:lang="en">Osawa H., Yamamoto H. Present and future status of flexible spectral imaging color enhancement and blue laser imaging technology // Dig. Endosc. - 2014. - 26 (Suppl. 1). - Р. 105-115.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Pohl J., Lotterer E., Balzer C. et al. Computed virtual chromoendoscopy versus standard colonoscopy with targeted indigocarmine chromoendoscopy: a randomized multicenter trial. Gut. - 2009. -58. - Р. 73-78.</mixed-citation><mixed-citation xml:lang="en">Pohl J., Lotterer E., Balzer C. et al. Computed virtual chromoendoscopy versus standard colonoscopy with targeted indigocarmine chromoendoscopy: a randomized multicenter trial. Gut. - 2009. -58. - Р. 73-78.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Pohl J., May A., Rabenstein T. et al. Computed virtual chromo-endoscopy: a new tool for enhancing tissue surface structures // Endoscopy. - 2007. - 39. - Р. 80-83.</mixed-citation><mixed-citation xml:lang="en">Pohl J., May A., Rabenstein T. et al. Computed virtual chromo-endoscopy: a new tool for enhancing tissue surface structures // Endoscopy. - 2007. - 39. - Р. 80-83.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Pohl J., May A., Rabenstein T. et al. Comparison of computed virtual chromoendoscopy and conventional chromoendoscopy with acetic acid for detection of neoplasia in Barrett’s esophagus // Endoscopy. - 2007. - 39. - Р. 594-598.</mixed-citation><mixed-citation xml:lang="en">Pohl J., May A., Rabenstein T. et al. Comparison of computed virtual chromoendoscopy and conventional chromoendoscopy with acetic acid for detection of neoplasia in Barrett’s esophagus // Endoscopy. - 2007. - 39. - Р. 594-598.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Rex D.K., Clodfelter R., Rahmani F et al. Narrow band imaging versus white light for the detection of proximal colon serrated lesions: a randomized, controlled trial // Gastrointest Endosc. - 2016. - 83D1. - Р. 166-171.</mixed-citation><mixed-citation xml:lang="en">Rex D.K., Clodfelter R., Rahmani F et al. Narrow band imaging versus white light for the detection of proximal colon serrated lesions: a randomized, controlled trial // Gastrointest Endosc. - 2016. - 83D1. - Р. 166-171.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Singh R., Jayanna M., Navadgi S. et al. Narrow-band imaging with dual focus magnification in differentiating colorectal neoplasia // Dig. Endosc. - 2015. - 25 suppl 2. - Р. 16-20.</mixed-citation><mixed-citation xml:lang="en">Singh R., Jayanna M., Navadgi S. et al. Narrow-band imaging with dual focus magnification in differentiating colorectal neoplasia // Dig. Endosc. - 2015. - 25 suppl 2. - Р. 16-20.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Snover D.C. Update on the serrated pathway to colorectal carcinoma // Hum. Pathol. - 2011. - 42. - Р. 1-10.</mixed-citation><mixed-citation xml:lang="en">Snover D.C. Update on the serrated pathway to colorectal carcinoma // Hum. Pathol. - 2011. - 42. - Р. 1-10.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Teixeira C.R., Torresini R.S., Canali C. et al. Endoscopic classification of the capillary-vessel pattern of the colorectal lesions by spectral estimation technology and magnifying zoom imaging // Gastrointest Endosc. - 2009. - 69 (3 Pt 2). - Р. 750-756.</mixed-citation><mixed-citation xml:lang="en">Teixeira C.R., Torresini R.S., Canali C. et al. Endoscopic classification of the capillary-vessel pattern of the colorectal lesions by spectral estimation technology and magnifying zoom imaging // Gastrointest Endosc. - 2009. - 69 (3 Pt 2). - Р. 750-756.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Vogelstein B., Fearon E.R., Hamilton S.R. et al. Genetic alterations during colo rectal tumor development // N. Engl. J. Med. - 1988. -319 (9). - Р. 525-532.</mixed-citation><mixed-citation xml:lang="en">Vogelstein B., Fearon E.R., Hamilton S.R. et al. Genetic alterations during colo rectal tumor development // N. Engl. J. Med. - 1988. -319 (9). - Р. 525-532.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Wanders L.K., Eat J.E., Uitentius S.E. et al. Diagnostic performance of narrowed spectrum endoscopy, autofluorescence imaging, and confocal laser endomicroscopy for optical diagnosis of colonic polyps: a meta-analysis // Lancet Oncol. - 2013. - 14. - Р. 1337-1347.</mixed-citation><mixed-citation xml:lang="en">Wanders L.K., Eat J.E., Uitentius S.E. et al. Diagnostic performance of narrowed spectrum endoscopy, autofluorescence imaging, and confocal laser endomicroscopy for optical diagnosis of colonic polyps: a meta-analysis // Lancet Oncol. - 2013. - 14. - Р. 1337-1347.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Wilson A., Saunders B.P. New paradigms in polypectomy: resect and discard, diagnose and disregard // Gastrointest Endosc. Clin. N. Am. - 2015. - 25D2. - Р. 287-302.</mixed-citation><mixed-citation xml:lang="en">Wilson A., Saunders B.P. New paradigms in polypectomy: resect and discard, diagnose and disregard // Gastrointest Endosc. Clin. N. Am. - 2015. - 25D2. - Р. 287-302.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Yoshida N., Yagi N., Inada Y. et al. Ability of a novel blue laser imaging system for the diagnosis of colorectal polyps // Dig. Endosc. - 2014. - 26 (2). - Р. 250-258.</mixed-citation><mixed-citation xml:lang="en">Yoshida N., Yagi N., Inada Y. et al. Ability of a novel blue laser imaging system for the diagnosis of colorectal polyps // Dig. Endosc. - 2014. - 26 (2). - Р. 250-258.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
